methyl-5-fluoro-2-methoxybenzenecarbimidothioate hydroiodide | 361548-87-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: methyl-5-fluoro-2-methoxybenzenecarbimidothioate hydroiodide
• 英文别名: methyl 5-fluoro-2-methoxybenzenecarboximidothioate;hydroiodide
• CAS: 361548-87-0
• 化学式: C₉H₁₀FNOS*HI
• 分子量: 327.161
• InChiKey: NTHYBFZAJQQAOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.14
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  58.4
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  5-fluoro-2-methoxybenzenecarbothioamide 、 碘甲烷 、 异丙醚 在 异丙醚 作用下， 以 丙酮 为溶剂， 反应 16.0h， 以to give methyl-5-fluoro-2-methoxybenzenecarbimidothioate hydroiodide (6.62 g) as rusty orange crystals的产率得到methyl-5-fluoro-2-methoxybenzenecarbimidothioate hydroiodide
  参考文献：
  名称：

  Novel amide compounds

  摘要：

  化合物的结构式（I）：R1-A-X-NHCO-Y-R2其中R1是杂环基团，可以有合适的取代基，或苯基，可以有合适的取代基，R2是紧缩苯基，可以有合适的取代基，苯基，可以有合适的取代基，或噻吩基，可以有合适的取代基，A是以下式子的基团：—（CH2）t—（O）m—或1其中R3和R4分别是氢或连接在一起形成亚胺，R5是氢或较低的烷基，t为0、1或2，p、m和n均为0或1，X是苯基，可以有合适的取代基，或含有氮的二价杂环基团，可以有合适的取代基，Y是键，较低的烷基，或较低的烯基，以及其盐。

  公开号：

  US20040087798A1

文献信息

• EP1264820
  申请人：——

  公开号：——

  公开（公告）日：——
• COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE
  申请人：Cohesion Technologies, Inc.

  公开号：EP1412404A1

  公开（公告）日：2004-04-28
• [EN] COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE<br/>[FR] COMPOSITIONS ET SYSTEMES DE FORMATION DE BIOMATERIAUX RETICULES ET PROCEDES DE PREPARATION ET D'UTILISATION ASSOCIES
  申请人：COHESION TECH INC

  公开号：WO2002102864A1

  公开（公告）日：2002-12-27

  Crosslinkable compositions are provided that readily crosslink in situ to provide biocompatible, nonimmunogenic crosslinked biomaterials. The compositions contain at least three biocompatible, nonimmunogenic components having reactive functional groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. In a preferred embodiment, a first component is polynucleophilic, a second component is polyelectrophilic, and at least one third component contains one or more functional groups reactive with the nucleophilic moieties one the first or second component. At least one of the components is a polyfunctional hydrophilic polymer; the other components may also comprise hydrophilic polymers, or they may be low molecular weight, typically hydrophobic, crosslinkers. Methods for preparing and using the compositions are also provided. Exemplary uses include tissue augmentation, biologically active agent delivery, bioadhesion, and prevention of adhesions following surgery or injury.
• Novel amide compounds
  申请人：——

  公开号：US20040087798A1

  公开（公告）日：2004-05-06

  A compound of the formula (I): R 1 -A-X-NHCO—Y—R 2 wherein R 1 is heterocyclic group which may have suitable substituents, or phenyl which may have suitable substituents, R 2 is condensed phenyl which may have suitable substituents, phenyl which may have suitable substituents, or thienyl which may have suitable substituents, A is a group of the formula: —(CH 2 ) t —(O) m — or 1 which R 3 and R 4 are each hydrogen or linked together to form imino, R 5 is hydrogen or lower alkyl, t is 0, 1 or 2, p, m and n are each 0 or 1, X is phenylene which may have suitable substituents, or bivalent heterocyclic group containing nitrogen which may have suitable substituents, Y is bond, lower alkylene, or lower alkenylene, and a salt thereof.

  化合物的结构式（I）：R1-A-X-NHCO-Y-R2其中R1是杂环基团，可以有合适的取代基，或苯基，可以有合适的取代基，R2是紧缩苯基，可以有合适的取代基，苯基，可以有合适的取代基，或噻吩基，可以有合适的取代基，A是以下式子的基团：—（CH2）t—（O）m—或1其中R3和R4分别是氢或连接在一起形成亚胺，R5是氢或较低的烷基，t为0、1或2，p、m和n均为0或1，X是苯基，可以有合适的取代基，或含有氮的二价杂环基团，可以有合适的取代基，Y是键，较低的烷基，或较低的烯基，以及其盐。