[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]methylphosphonic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]methylphosphonic acid
• 化学式: C₇H₁₅O₈P
• 分子量: 258.16
• InChiKey: XRMRHVWWWWFMKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.8
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  148
• 氢给体数：
  6
• 氢受体数：
  8

文献信息

• Methods and compositions to treat glycosaminoglycan-associated molecular interactions
  申请人：Kisilevsky Robert

  公开号：US20070078082A1

  公开（公告）日：2007-04-05

  Therapeutic compounds and methods for inhibiting a glycosaminoglycan (GAG)-associated molecular interaction in a subject, whatever its clinical setting, are described
• Compounds and methods for modulating cerebral amyloid angiopathy
  申请人：Green Allan M.

  公开号：US20080317834A1

  公开（公告）日：2008-12-25

  The invention provides methods of inhibiting cerebral amyloid angiopathy. The invention further provides methods of treating a disease state characterized by cerebral amyloid angiopathy in a subject.