2,3,4,5,6,7,8-Heptahydroxyoctanoic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,4,5,6,7,8-Heptahydroxyoctanoic acid
• 化学式: C₈H₁₆O₉
• 分子量: 256.21
• InChiKey: VMAMIMWJAKTQSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.6
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  179
• 氢给体数：
  8
• 氢受体数：
  9

文献信息

• TOPICAL ANTIVIRAL COMPOSITIONS
  申请人：Topical Remedy, LLC

  公开号：EP3344265A1

  公开（公告）日：2018-07-11
• [EN] TOPICAL ANTIVIRAL COMPOSITIONS<br/>[FR] COMPOSITIONS ANTIVIRALES TOPIQUES
  申请人：TOPICAL REMEDY LLC

  公开号：WO2017040844A1

  公开（公告）日：2017-03-09

  In various embodiments compositions that inactivates a virus or inhibit replication of a virus are provided where the compositions comprise a C1-C10 alcohol; an acid selected from the group consisting of gallic acid, methyl gallate, 3, 4-dihydroxy benzoic acid, p-hydroxy benzoic acid, vanillic acid, p-coumaric acid, ferulic acid, syringic acid, salicylic acid, luteic acid, and eudesmic acid; and a pharmaceutically acceptable carrier; where the pH of said composition is pH 4.5 or lower. In certain embodiments the alcohol comprises one or more alcohols selected from the group consisting of ethanol, ethanol, 2-propanol, 1-propanol, 2,3-butanediol, 1,2-butanediol, 1,3-butanediol, and 1,4-butanediol, butyl alcohol (including n-butanol, sec-butanol, isobutanol, tert-butanol), pentanol, hexadecan-1-ol, ethane-1,2-diol, propane-1,2-diol, propane-1,2,3-triol, butane-1,2,3,4-tetraol, pentane-1,2,3,4,5-pentol, hexane-1,2,3,4,5,6-hexol, heptane-1,2,3,4,5,6,7-heptol, prop-2-ene-1-ol, 3,7-dimethylocta-2,6-dien-1-ol, prop-2-in-1-ol, cyclohexane-1,2,3,4,5,6-hexol, and 2-(2-propyl)-5-methyl-cyclohexane-1-ol.