1,3,3-triethoxy-1-(n-propoxy)propane | 603151-67-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,3,3-triethoxy-1-(n-propoxy)propane
• 英文别名: 1,1,3-Triethoxy-3-propoxypropane
• CAS: 603151-67-3
• 化学式: C₁₂H₂₆O₄
• 分子量: 234.336
• InChiKey: ZAOIJYNZJGBTRJ-UHFFFAOYSA-N

物化性质

• 沸点：
  277.7±40.0 °C(Predicted)
• 密度：
  0.926±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  正丙基乙烯基醚 、 原甲酸三乙酯 在 iron(III) chloride 作用下， 反应 6.0h， 以28%的产率得到1,3,3-triethoxy-1-(n-propoxy)propane
  参考文献：
  名称：

  EP1607381

  摘要：

  公开号：

文献信息

• PROCESS FOR PRODUCING TETRAALKOXYPROPANE AND DERIVATIVE THEREOF
  申请人：NIPPON CARBIDE KOGYO KABUSHIKI KAISHA

  公开号：EP1607381A1

  公开（公告）日：2005-12-21

  In view of the fact that a methyl vinyl ether, which is useful as a starting material for the synthesis of tetraalkoxypropane useful as a skeleton-forming agent having a high reactivity usable as a starting material, etc. for a pharmaceutical and agrochemical intermediates such as a pyrazole derivative or pyrimidine derivative, particularly 1,1,3,3-tetramethoxypropane, is in a gaseous state and difficult to use for industrial production, tetraalkoxypropane useful as a skeleton-forming agent for a pharmaceutical and agrochemical intermediate such as a pyrazole derivative or pyrimidine derivative is easily produced on an industrial scale by using the industrially useable propoxyvinyl ether, as a starting material, without using a gaseous state methyl vinyl ether.

  鉴于甲基乙烯基醚可用作合成四烷氧基丙烷的起始原料，而四烷氧基丙烷可用作骨架形成剂，具有高反应活性，可用作医药和农用化学品中间体（如吡唑衍生物或嘧啶衍生物）的起始原料等。四烷氧基丙烷是医药和农用化学品的中间体，如吡唑衍生物或嘧啶衍生物，特别是 1,1,3,3 四甲氧基丙烷，呈气态，难以用于工业生产、而作为医药和农用化学品中间体（如吡唑衍生物或嘧啶衍生物）骨架形成剂的四烷氧基丙烷，使用工业上可用的丙氧基乙烯基醚作为起始原料，而不使用气态的甲基乙烯基醚，则很容易进行工业化生产。
• Process for producing tetraalkoxypropane and derivative thereof
  申请人：Mita Shinya

  公开号：US20060183948A1

  公开（公告）日：2006-08-17

  In view of the fact that a methyl vinyl ether, which is useful as a starting material for the synthesis of tetraalkoxypropane useful as a skeleton-forming agent having a high reactivity usable as a starting material, etc. for a pharmaceutical and agrochemical intermediates such as a pyrazole derivative or pyrimidine derivative, particularly 1,1,3,3-tetramethoxypropane, is in a gaseous state and difficult to use for industrial production, tetraalkoxypropane useful as a skeleton-forming agent for a pharmaceutical and agrochemical intermediate such as a pyrazole derivative or pyrimidine derivative is easily produced on an industrial scale by using the industrially useable propoxyvinyl ether, as a starting material, without using a gaseous state methyl vinyl ether.

  鉴于甲基乙烯基醚可用作合成四烷氧基丙烷的起始原料，而四烷氧基丙烷可用作骨架形成剂，具有高反应活性，可用作医药和农用化学品中间体（如吡唑衍生物或嘧啶衍生物）的起始原料等。四烷氧基丙烷是医药和农用化学品的中间体，如吡唑衍生物或嘧啶衍生物，特别是 1,1,3,3 四甲氧基丙烷，呈气态，难以用于工业生产、而作为医药和农用化学品中间体（如吡唑衍生物或嘧啶衍生物）骨架形成剂的四烷氧基丙烷，使用工业上可用的丙氧基乙烯基醚作为起始原料，而不使用气态的甲基乙烯基醚，则很容易进行工业化生产。
• Use of Compounds for the Preservation of the Human or Animal Body and Compositions Comprising Same
  申请人：DuBois Jean-Luc

  公开号：US20080166315A1

  公开（公告）日：2008-07-10

  The present invention relates to the use of at least one compound of formula (I) R—(OCH 2 )n—OR′ in which R and R′, identical or different, represent a linear or branched alkyl radical comprising 1 to 5 carbon atoms and n is an index with a value comprised between 1 and 8, and/or at least one dialdehyde acetal type compound for the preservation of the human or animal body and/or the embalming of dead bodies. It also relates to a composition comprising same and a process for preserving a human or animal body and/or embalming a dead body comprising the administration of the composition to the dead body in particular by injection, perfusion, immersion or topical application.
• EP1607381
  申请人：——

  公开号：——

  公开（公告）日：——