3-(Dihydroxymethyl)pentane-1,1,3,5,5-pentol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-(Dihydroxymethyl)pentane-1,1,3,5,5-pentol
• 化学式: C₆H₁₄O₇
• 分子量: 198.17
• InChiKey: SQKCGPGTPCENAH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.5
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  142
• 氢给体数：
  7
• 氢受体数：
  7

文献信息

• PROCESS FOR PRODUCTION OF SURFACE-COATED INORGANIC PARTICLES
  申请人：Tokyo Institute of Technology

  公开号：EP2184262A1

  公开（公告）日：2010-05-12

  Nano-sized inorganic particles having uniform particle sizes and precisely controlled particle diameters have already been produced by synthesis in an organic solvent, but these nano-sized inorganic particles are hindered from dispersing in a polar solvent because of the adsorption of a long-chain fatty acid on the surfaces of the particles. Further, it was difficult to form nano-sized inorganic particles dispersible in a polar solvent by replacing the long-chain fatty acid coats. According to the invention, various surface-coated inorganic particles dispersible in polar solvents can be produced from fatty acid-coated inorganic particles by adding a temporary coating substance such as thiomalic acid to a nonpolar solvent containing fatty acid-coated inorganic particles dispersed therein to replace the fatty acid coats by the temporary coating substance, dispersing the inorganic particles coated with the temporary coating substance in a polar solvent, and then adding a coating substance dispersible in a polar solvent, e.g., citric acid to the obtained dispersion to replace the temporary coating substance coats covering the inorganic particles by the coating substance dispersible in a polar solvent.

  人们已经通过在有机溶剂中合成的方法制备出了粒度均匀、粒径可精确控制的纳米级无机颗粒，但这些纳米级无机颗粒在极性溶剂中分散受阻，原因是颗粒表面吸附了长链脂肪酸。此外，很难通过替换长链脂肪酸涂层来形成可在极性溶剂中分散的纳米级无机颗粒。根据本发明，可从脂肪酸包覆的无机颗粒制备可分散在极性溶剂中的各种表面包覆无机颗粒，具体方法是：在含有分散在其中的脂肪酸包覆无机颗粒的非极性溶剂中加入硫代苹果酸等临时包覆物质，用临时包覆物质取代脂肪酸包覆层，将包覆有临时包覆物质的无机颗粒分散在极性溶剂中，然后在得到的分散液中加入可分散在极性溶剂中的包覆物质，如柠檬酸、将可分散在极性溶剂中的包覆物质（如柠檬酸）加入所得到的分散液中，以取代包覆无机颗粒的临时包覆物质。
• US8852555B2
  申请人：——

  公开号：US8852555B2

  公开（公告）日：2014-10-07