2-acetamido-N-[(2S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷
• 英文名称: 2-acetamido-N-[(2S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide
• 化学式: C₂₄H₃₁N₇O₆
• 分子量: 513.5
• InChiKey: LADKVYSQIGJMFP-UAAYVULCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  37
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  164
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• [EN] METHODS OF PANCREATIC DIFFERENTIATION OF STEM CELLS<br/>[FR] MÉTHODES DE DIFFÉRENCIATION PANCRÉATIQUE DE CELLULES SOUCHES
  申请人：UNIV CALIFORNIA

  公开号：WO2018119155A1

  公开（公告）日：2018-06-28

  Disclosed herein are methods relating to differentiation of stem cells into pancreatic cells in vitro. Also disclosed are cells and populations of cells produced according to the disclosed methods. Further provided are methods of treating pancreas-related diseases or conditions using cells produced according to the disclosed methods.