N,O6-Disulfo-Glucosamine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N,O6-Disulfo-Glucosamine
• 英文别名: [(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(sulfooxymethyl)oxan-3-yl]sulfamic acid
• 化学式: C₆H₁₃NO₁₁S₂
• 分子量: 339.3
• InChiKey: DQTRACMFIGDHSN-UKFBFLRUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  217
• 氢给体数：
  6
• 氢受体数：
  12

文献信息

• Orthoester derivatives of crown ethers as carriers for pharmaceutical and diagnostic compositions
  申请人：ArisGen SA

  公开号：EP2332929A1

  公开（公告）日：2011-06-15

  This invention relates to A crown ether of formula (I) wherein m is 4, 5, 6, 7, or 8 and i is, independently for each occurrence, 1 or 2; at least one occurrence in the crown ether of R1, R2 and the carbon to which R1 and R2 are attached, said carbon being bound directly to an ether oxygen of formula (I), form together a group of formula (II) wherein L is a linker which is absent or selected from a covalent bond and (CR5R6)n, useful as carriers for pharmaceutical and diagnostic compositions.

  这项发明涉及一种式(I)的冠醚，其中m为4、5、6、7或8，i为每次出现时独立取1或2；在冠醚中至少有一个R1、R2和R1和R2附着的碳形成一个式(II)的基团，其中L是一个连接物，可以是缺席或选择自共价键和(CR5R6)n，用作药物和诊断组合物的载体。
• [EN] ORTHOESTER DERIVATIVES OF CROWN ETHERS AS CARRIERS FOR PHARMACEUTICAL AND DIAGNOSTIC COMPOSITIONS<br/>[FR] DÉRIVÉS ORTHO-ESTERS D'ÉTHERS-COURONNES COMME VÉHICULES POUR DES COMPOSITIONS PHARMACEUTIQUES ET DIAGNOSTIQUES
  申请人：ARISGEN SA

  公开号：WO2011064300A1

  公开（公告）日：2011-06-03

  This invention relates to A crown ether of formula (I) wherein m is 4, 5, 6, 7, or 8 and i is, independently for each occurrence, 1 or 2; at least one occurrence in the crown ether of R1, R2 and the carbon to which R1 and R2 are attached, said carbon being bound directly to an ether oxygen of formula (I), form together a group of formula (II) wherein L is a linker which is absent or selected from a covalent bond and (CR5R6)n, useful as carriers for pharmaceutical and diagnostic compositions.

  这项发明涉及一种式（I）的冠醚，其中m为4、5、6、7或8，i对于每次出现独立取1或2；在冠醚中至少有一个发生在R1、R2和R1和R2连接的碳之间，所述碳直接与式（I）的醚氧结合，共同形成式（II）的基团，其中L是一个连接物，可以是不存在或从共价键和（CR5R6）n中选择的，用作药物和诊断组合物的载体。
• Active agent delivery systems and methods for protecting and administering active agents
  申请人：New River Pharmaceuticals Inc.

  公开号：US20040063628A1

  公开（公告）日：2004-04-01

  The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.

  本发明涉及活性物质输送系统，更具体地涉及包含氨基酸，作为单个氨基酸或肽的组成部分，与活性物质共价连接的组合物和用于给予共轭活性物质组合物的方法。
• ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS
  申请人：Mickle Travis

  公开号：US20090253792A1

  公开（公告）日：2009-10-08

  The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.

  本发明涉及活性剂递送系统，更具体地涉及包含氨基酸（作为单个氨基酸或肽）与活性剂共价连接的组合物以及给予共轭活性剂组合物的方法。
• ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS
  申请人：Mickle Travis

  公开号：US20090306228A1

  公开（公告）日：2009-12-10

  The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.

  本发明涉及活性剂递送系统，更具体地涉及包含氨基酸，作为单个氨基酸或肽，与活性剂共价结合的组合物以及用于给予共轭活性剂组合物的方法。