3-O-sulfo-beta-D-galactopyranose | 134224-05-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-O-sulfo-beta-D-galactopyranose
• 英文别名: [(2R,3R,4S,5S,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl] hydrogen sulfate
• CAS: 134224-05-8
• 化学式: C₆H₁₂O₉S
• 分子量: 260.22
• InChiKey: HHRMGTRTCHNCRO-FDROIEKHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  162
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• Sulfated and phosphated saccharide derivatives, process for the preparation of the same and use thereof
  申请人：SANWA KAGAKU KENKYUSHO CO., LTD.

  公开号：EP0771815A1

  公开（公告）日：1997-05-07

  There are described sulfate or phosphate saccharide derivatives of the Formula    wherein R1 is hydrogen atom or a residue of sulfate, phosphate or L-fucose; R2, R3 and R4 are hydrogen atom or a residue of sulfate or phosphate, respectively; l is an integer of 0 or 1; m is an integer of 0 - 15; and n is an integer of 0 - 21, or pharmaceutically acceptable salts thereof, a process for the preparation of the derivatives and salts as well as use thereof, as an anti-inflammatory agent.

  该文描述了化学式为   的硫酸盐或磷酸盐葡萄糖衍生物，其中R1为氢原子或硫酸盐、磷酸盐或L-岩藻糖残基；R2、R3和R4分别为氢原子或硫酸盐或磷酸盐残基；l为0或1的整数；m为0-15的整数；n为0-21的整数，或其药学上可接受的盐。该文还描述了制备这些衍生物和盐的方法以及将其用作抗炎药的用途。
• Compositions comprising a core-1 positive microorganism and their use for the treatment or prophylaxis of tumors
  申请人：Glycotope GmbH

  公开号：EP1920781A1

  公开（公告）日：2008-05-14

  The present invention relates to the field of prevention and treatment of gastrointestinal disorders. More particularly, the present invention relates to the prevention and treatment of Core-1-positive carcinomas. It relates to coreotics and a method of producing the same and to a method of prevention and treatment of core-1 positive disorders using the same.

  本发明涉及胃肠道疾病的预防和治疗领域。更具体地说，本发明涉及核心-1 阳性癌的预防和治疗。本发明涉及核心素及其生产方法，以及使用核心素预防和治疗核心-1 阳性疾病的方法。
• Novel glycosylated peptide target in neoplastic cells
  申请人：Patrys Limited

  公开号：EP2431053A1

  公开（公告）日：2012-03-21

  The invention provides polypeptide, nucleic acid and other compositions. Polypeptide, nucleic acid and other compositions are useful in treatment and diagnostic methods. One treatment method includes inhibiting growth or proliferation of hyperproliferative cells or inducing regression of hyperproliferative cells, such as cells of a cellular hyperproliferative disorder, or reducing levels of LDL or oxLDL.

  本发明提供了多肽、核酸和其他组合物。多肽、核酸和其他组合物可用于治疗和诊断方法。一种治疗方法包括抑制过度增殖细胞的生长或增殖，或诱导过度增殖细胞（如细胞过度增殖症细胞）消退，或降低低密度脂蛋白或氧化低密度脂蛋白的水平。
• MICROORGANISMS OF FRACTIONS THEREOF CAPABLE OF ACTIVATING CELLULAR IMMUNITY AGAINST CARBOHYDRATES
  申请人：Glycotope GmbH

  公开号：EP2099480A2

  公开（公告）日：2009-09-16
• NOVEL GLYCOSYLATED PEPTIDE TARGET IN NEOPLASTIC CELLS
  申请人：PATRYS LIMITED

  公开号：EP2101813A2

  公开（公告）日：2009-09-23