4-O-Methyl-alpha-D-glucuronic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-O-Methyl-alpha-D-glucuronic acid
• 英文别名: (2S,3S,4R,5R,6S)-4,5,6-trihydroxy-3-methoxyoxane-2-carboxylic acid
• 化学式: C₇H₁₂O₇
• 分子量: 208.17
• InChiKey: WGLLPAPKWFDHHV-NRGGUMNKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.4
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• METHOD AND ENZYMATIC PREPARATION FOR TREATMENT OF CELLULOSE PULPS
  申请人：——

  公开号：US20040069426A1

  公开（公告）日：2004-04-15

  The present invention concerns a method for enzymatic treatment of lignocellulosic materials which contain xylan-polymers, such as cellulose kraft pulps. According to a method of the present kind, at least a part of the hexenuronic acid groups present in the material is selectively removed in order to remove metal ions from the pulp, to change the surface charge thereof, to improve the brightness stability of the pulp and to render the material more suitable for enzymatic treatment.

  本发明涉及一种用于酶处理含有木聚糖聚合物的木质纤维素材料的方法，例如纤维素卡夫特浆。根据本发明的一种方法，选择性地去除材料中存在的至少一部分六羟基脂肪酸基团，以从纸浆中去除金属离子，改变其表面电荷，提高纸浆的亮度稳定性，并使材料更适合酶处理。
• Advanced drug development and manufacturing
  申请人：Los Alamos National Security, LLC

  公开号：EP2511844A2

  公开（公告）日：2012-10-17

  There is described an apparatus for measuring protein characteristics comprising an X-ray fluorescence (XRF) spectrometer comprising a source of polychromatic X-rays, an X-ray detector, a protein, a molecule that has been exposed to and at least weakly binds to the protein, a plurality of X-ray fluorescence signal data obtained by irradiating chemical elements in the protein and molecule with the polychromatic X-rays and a security system for maintaining records for the data from the plurality of X-ray fluorescence signal measurements. There is also described an x-ray microscope for measuring a sample.

  描述了一种测量蛋白质特性的仪器，该仪器包括一个 X 射线荧光 (XRF) 光谱仪，其中包括一个多色 X 射线源、一个 X 射线探测器、一个蛋白质、一个已暴露于该蛋白质并至少与该蛋白质弱结合的分子、通过用多色 X 射线照射蛋白质和分子中的化学元素而获得的多个 X 射线荧光信号数据，以及一个用于维护多个 X 射线荧光信号测量数据记录的安全系统。此外，还介绍了一种用于测量样品的 X 射线显微镜。
• PHARMACEUTICAL COMPOSITION CONSISTING OF BLAUTIA, FOR ORAL ADMINISTRATION
  申请人：Evelo Biosciences, Inc.

  公开号：EP3747450A1

  公开（公告）日：2020-12-09

  Probiotic compositions containing non-pathogenic microbial entities, e. g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prehiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.

  本文描述了含有非致病性微生物实体（如细菌实体）的益生菌组合物。益生菌组合物可选择性地含有一种或多种预益生菌或与之结合使用。还提供了益生菌组合物治疗或预防受试者局部或全身微生物组紊乱的用途。
• Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
  申请人：Evelo Biosciences, Inc.

  公开号：US10869903B2

  公开（公告）日：2020-12-22

  Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.

  本文描述了含有非致病性微生物实体（如细菌或真菌实体）的益生菌组合物。益生菌组合物可选择含有一种或多种益生元或与之结合使用。还提供了益生菌组合物治疗或预防移植失调的用途，例如移植抗宿主疾病（GVHD）。
• Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome
  申请人：Evelo Biosciences, Inc.

  公开号：US10980845B2

  公开（公告）日：2021-04-20

  Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.

  本文描述了含有非致病性微生物实体（如细菌实体）的益生菌组合物。益生菌组合物可选择含有一种或多种益生元或与之结合使用。还提供了益生菌组合物治疗或预防受试者局部或全身微生物组紊乱的用途。