2-[2-(2-Isopentoxyethoxy)ethoxy]ethanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-(2-Isopentoxyethoxy)ethoxy]ethanol
• 英文别名: 2-[2-[2-(3-methylbutoxy)ethoxy]ethoxy]ethanol
• 化学式: C₁₁H₂₄O₄
• 分子量: 220.31
• InChiKey: KEMFXYQWQLPSQF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  15
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• PRODRUG BIPYRIDYLAMINOPYRIDINES AS SYK INHIBITORS
  申请人：HAIDLE Andrew M.

  公开号：US20150299125A1

  公开（公告）日：2015-10-22

  The present invention provides compounds of Formula (I), which are prodrugs of trans-4-[(1R)-(6-[4-(difluoromethyl)pyridin-2-yl]amino}-4-methyl-2,3′-bipyridin-6′-yl)-1-hydroxyethyl]cyclohexanecarboxylic acid, a potent inhibitor of Syk. The compounds are useful in the treatment and prevention of diseases mediated by the enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.

  本发明提供了式（I）的化合物，它们是trans-4-[(1R)-(6-[4-(二氟甲基)吡啶-2-基]氨基}-4-甲基-2,3′-联苯并[6′]-基)-1-羟基乙基]环己烷羧酸的前药，是Syk的有效抑制剂。这些化合物在治疗和预防由该酶介导的疾病，如哮喘、COPD、类风湿性关节炎和癌症方面是有用的。
• Pretreatment fluids with ammonium metal chelate cross-linker for printing media
  申请人：Sarkisian George

  公开号：US10144830B2

  公开（公告）日：2018-12-04

  A pretreatment fluid for printing media with a pigment ink composition includes a liquid vehicle, at least one polymeric binder having pendant carboxyl groups, and an ammonium metal chelate cross-linker.

  用于使用颜料油墨组合物印刷介质的预处理液包括液体载体、至少一种具有悬垂羧基的聚合物粘合剂和金属螯合铵交联剂。
• Illumination device and vehicle glass utilization method
  申请人：Sekisui Chemical Co., Ltd.

  公开号：US11203184B2

  公开（公告）日：2021-12-21

  A lighting device includes a light source configure to irradiate excitation light and a vehicle glass configured to emit visible light through incident radiation of the excitation light, in which the vehicle glass is configured to emit the visible light synchronously in an area of 30% or more by irradiation with the excitation light.

  一种照明设备包括一个配置为照射激发光的光源和一个配置为通过激发光的入射辐射发射可见光的车载玻璃，其中车载玻璃配置为通过激发光的照射在 30% 或更大的区域内同步发射可见光。
• Self-assembling dyes
  申请人：Agfa Graphics N.V.

  公开号：EP1486539B1

  公开（公告）日：2009-08-26
• Polymeric particles capable of absorbing blood and/or body fluids
  申请人：Ziemer Antje

  公开号：US20070112222A1

  公开（公告）日：2007-05-17

  Polymeric particles capable of absorbing blood and/or body fluids, the polymeric particles being coated with at least one surfactant and with at least one solvent, are produced and used for absorbing blood and/or body fluids, especially in hygiene articles.