Methyl 2-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methylenecyclopentanecarboxylate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl 2-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methylenecyclopentanecarboxylate
• 英文别名: methyl 2-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methylidenecyclopentane-1-carboxylate
• 化学式: C₁₃H₂₀O₄
• 分子量: 240.29
• InChiKey: FIUCILXVUSEGEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• INHIBITORS OF NEURAMINIDASES
  申请人：ABBOTT LABORATORIES

  公开号：EP1087938A1

  公开（公告）日：2001-04-04
• US6518305B1
  申请人：——

  公开号：US6518305B1

  公开（公告）日：2003-02-11
• [EN] INHIBITORS OF NEURAMINIDASES<br/>[FR] INHIBITEURS DE NEURAMINIDASES
  申请人：ABBOTT LABORATORIES

  公开号：WO1999054290A1

  公开（公告）日：1999-10-28

  (EN) Disclosed are compounds of formula (I), (II) or (III), which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.(FR) L'invention concerne les composés représentés par les formule (I), (II) et (III). Ces composés servent à inhiber les neuraminidases dans des micro-organismes pathogènes, en particulier la neuraminidase de la grippe. L'invention concerne également des compositions et des procédés permettant de prévenir et de traiter les maladies causées par des micro-organismes comprenant une neuraminidase, des procédés de préparation de ces composés et des intermédiaires de synthèse utilisés dans ces procédés.
• [EN] INHIBITORS OF NEURAMINIDASES<br/>[FR] INHIBITEURS DES NEURAMINIDASES
  申请人：ABBOTT LAB

  公开号：WO2001028979A2

  公开（公告）日：2001-04-26

  Disclosed are compounds of formula (I), (II) or (III) which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.