1,2,4-trimethoxy-butane | 20637-48-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,2,4-trimethoxy-butane
• 英文别名: 1,2,4-Trimethoxybutane
• CAS: 20637-48-3
• 化学式: C₇H₁₆O₃
• 分子量: 148.202
• InChiKey: CWLPBGQUGHLPBK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF
  申请人：Pedersen Erik Bjerregaard

  公开号：US20110130557A1

  公开（公告）日：2011-06-02

  There is provided an intercalating oligonucleotide for stabilizing natural or modified DNA and RNA triplexes, duplexes and hybrids thereof having the general structure (I) triplex forming oligonucleotides of the invention are capable of binding specifically to double stranded target nucleic acids and are therefore of interest for modulation of the activity of target nucleic acids and also detection of target nucleic acids.

  本发明提供了一种插入寡核苷酸，用于稳定天然或修饰的DNA和RNA三联体、双联体和杂交体，其具有一般结构（I）。本发明的三联体形成寡核苷酸能够特异性地结合到双链目标核酸，因此对于调节目标核酸的活性和检测目标核酸也具有兴趣。
• Methods and Systems for Isolating Target Molecules from Complex Solutions by Column-Chromatography Using Eluants Containing Organic Solvents
  申请人：Zhou Joe Xin Hua

  公开号：US20100130727A1

  公开（公告）日：2010-05-27

  Various system and method embodiments of the present invention are directed to separating target molecules from complex solutions by affinity column chromatography using organic-solvent-containing eluants. In one embodiment of the present invention, an eluant containing an organic-solvent is used, at a first pH, to remove non-target solutes and suspended entities from an affinity chromatography column. The pH of the eluant is then changed to a second pH, and the organic-solvent-containing eluant is used to elute target molecules from the affinity column chromatography.