ethyl-arabinofuranoside

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: ethyl-arabinofuranoside
• 英文别名: Aethyl-arabinofuranosid；Ethyl beta-d-riboside；2-ethoxy-5-(hydroxymethyl)oxolane-3,4-diol
• 化学式: C₇H₁₄O₅
• 分子量: 178.185
• InChiKey: XESKOQZTIQOBMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Human helicase DDX3 inhibitors as therapeutic agents
  申请人：AZIENDA OSPEDALIERA UNIVERSITARIA SENESE

  公开号：US10941121B2

  公开（公告）日：2021-03-09

  The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.

  本发明是指具有式 I 和 II 的 RNA 螺旋酶 DDX3 抑制活性的化合物及其治疗用途，特别是用于治疗病毒性疾病。
• Use of DDX3 inhibitors as antiproliferative agents
  申请人：AZIENDA OSPEDALIERA UNIVERSITARIA SENESE

  公开号：US11000512B2

  公开（公告）日：2021-05-11

  The present invention refers to compounds of formula I or II endowed with DDX3 inhibitory activity, relative pharmaceutical compositions and their use as antihyperproliferative agents. (I) or (II).

  本发明涉及具有 DDX3 抑制活性的式 I 或式 II 化合物、相关药物组合物及其作为抗过增殖剂的用途。(I)或(II)。
• USE OF DDX3 INHIBITORS AS ANTIPROLIFERATIVE AGENTS
  申请人：AZIENDA OSPEDALIERA UNIVERSITARIA SENRESE

  公开号：US20190099403A1

  公开（公告）日：2019-04-04

  The present invention refers to compounds of formula I or II endowed with DDX3 inhibitory activity, relative pharmaceutical compositions and their use as antihyperproliferative agents. (I) or (II)
• HUMAN HELICASE DDX3 INHIBITORS AS THERAPEUTIC AGENTS
  申请人：AZIENDA OSPEDALIERA UNIVERSITARIA SENESE

  公开号：US20200140398A1

  公开（公告）日：2020-05-07

  The present invention refers to compounds endowed with RNA helicase DDX3 inhibitory activity of formula I and II and their therapeutic use, in particular for the treatment of viral diseases.
• [EN] USE OF O-GLYCOSYLATED INDOLE OR INDOLINE DERIVATIVE WITH GLYCOSIDASE FOR DEYING KERATIN FIBERS<br/>[FR] UTILISATION D'UN DÉRIVÉ D'INDOLE OU D'INDOLINE O-GLYCOSYLÉ AVEC UNE GLYCOSIDASE POUR COLORER DES FIBRES DE KÉRATINE
  申请人：OREAL

  公开号：WO2017182340A1

  公开（公告）日：2017-10-26

  A subject of the invention is the use of i) hydroxyindol(in)e derivative(s) glycosylated on at least one hydroxyl group, in the presence of at least ii) one enzyme with glycosidase activity, in particular beta-glycosidase activity, more particularly glucosidase activity and even more particularly beta-glucosidase activity, for treating keratin fibres, in particular dyeing human keratin fibres such as the hair, preferably dyeing said fibres. A subject of the invention is also a process for treating keratin fibres using i), ii) and a kit comprising the ingredients i) and ii). The process according to the invention has the advantage of dyeing human keratin fibres, with powerful or chromatic dyeing results that are resistant to washing, perspiration, sebum andlight, and that are moreover long-lasting, without impairing said fibres. Furthermore, the colourations obtained from the process give uniform colours from the root to the tip of a fibre (low colouration selectivity). In addition, the compositions comprising the i) hydroxyindol(in)e derivative(s) glycosylated on at least one of the hydroxyl groups degrade very little in air and remain stable with respect to storage.