5-(Hydroxymethyl)-2,4-dimethoxyoxolan-3-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-(Hydroxymethyl)-2,4-dimethoxyoxolan-3-ol
• 化学式: C₇H₁₄O₅
• 分子量: 178.18
• InChiKey: YGAVQJVFQKBFHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  68.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• MULTI-FUNCTIONAL MICRO AND NANOPARTICLES FOR USE IN ROOT CANAL THERAPIES
  申请人：THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

  公开号：US20180185249A1

  公开（公告）日：2018-07-05

  Chitosan nanoparticles are provided for use in the in vivo treatment of connective tissues in root canal therapies. The nanoparticles are optionally linked with one or more photoactivatable compounds for providing antibactenal/antibiofilm properties, neutralizing bacterial byproducts and/or chemical/photodynamic crosslinking to achieve enhanced mechanical properties, chemical stability in connective tissues and/or to improve surface/interfacial integrity between filling material and connective tissue.