1,3-Dioxo-2-{4-[(2-oxo-2-phenylethoxy)carbonyl]phenyl}isoindoline-5-carboxylic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,3-Dioxo-2-{4-[(2-oxo-2-phenylethoxy)carbonyl]phenyl}isoindoline-5-carboxylic acid
• 英文别名: 1,3-dioxo-2-(4-phenacyloxycarbonylphenyl)isoindole-5-carboxylic acid
• 化学式: C₂₄H₁₅NO₇
• 分子量: 429.4
• InChiKey: RQEMPLKVXLHJAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  32
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  118
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases
  申请人：Hannus Michael

  公开号：US20090324580A1

  公开（公告）日：2009-12-31

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.
• USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES
  申请人：HANNUS MICHAEL

  公开号：US20120276121A1

  公开（公告）日：2012-11-01

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.
• US8507546B2
  申请人：——

  公开号：US8507546B2

  公开（公告）日：2013-08-13