3-Methylene-bicyclo[3.2.1]oct-6-en-8-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Methylene-bicyclo[3.2.1]oct-6-en-8-ol
• 英文别名: 3-methylidenebicyclo[3.2.1]oct-6-en-8-ol
• 化学式: C₉H₁₂O
• 分子量: 136.19
• InChiKey: OXIJSZPSBBWHKJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID
  申请人：Visolis, Inc.

  公开号：US20160145227A1

  公开（公告）日：2016-05-26

  The invention relates to a process comprising reacting mevalonic acid, or a solution comprising mevalonic acid, to yield a first product or first product mixture, optionally in the presence of a solid catalyst and/or at elevated temperature and/or pressure. The invention further relates to a process comprising: (a) providing a microbial organism that expresses a biosynthetic mevalonic acid pathway; (b) growing the microbial organism in fermentation medium comprising suitable carbon substrates, whereby biobased mevalonic acid is produced; and (c) reacting said biobased mevalonic acid to yield a first product or first product mixture.

  这项发明涉及一种过程，包括将甲烷酸或含有甲烷酸的溶液反应，以产生第一产品或第一产品混合物，可选地在固体催化剂的存在下和/或在升高的温度和/或压力下。该发明还涉及一种过程，包括：(a)提供表达生物合成甲烷酸途径的微生物生物体；(b)在包含适当碳基底物的发酵培养基中培养微生物生物体，从而产生生物基甲烷酸；以及(c)将所述生物基甲烷酸反应，以产生第一产品或第一产品混合物。
• Processes for conversion of biologically derived mevalonic acid
  申请人：Visolis, Inc.

  公开号：US10208008B2

  公开（公告）日：2019-02-19

  A process is provided for converting mevalonic acid into various useful products and derivatives. More particularly, the process comprises reacting mevalonic acid, or a solution comprising mevalonic acid, in the presence of a solid catalyst at an elevated temperature and pressure to thereby form various biobased products. The process may also comprise: (a) providing a microbial organism that expresses a biosynthetic mevalonic acid pathway; (b) growing the microbial organism in fermentation medium comprising suitable carbon substrates, whereby biobased mevalonic acid is produced; and (c) reacting the biobased mevalonic acid in the presence of a solid catalyst at an elevated temperature and pressure to yield various biobased products.

  提供了一种将甲羟戊酸转化为各种有用产品和衍生物的工艺。更具体地说，该工艺包括在固体催化剂存在下，在高温高压下使甲羟戊酸或包含甲羟戊酸的溶液发生反应，从而形成各种生物基产品。该工艺还可包括：(a) 提供表达生物合成甲羟戊酸途径的微生物有机体；(b) 在包含适当碳底物的发酵培养基中培养微生物有机体，从而产生生物基甲羟戊酸；(c) 在固体催化剂存在下，在高温高压下反应生物基甲羟戊酸，生成各种生物基产品。