Phenyl-[1-(pyridin-2-ylmethyl)pyridin-1-ium-4-yl]methanone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Phenyl-[1-(pyridin-2-ylmethyl)pyridin-1-ium-4-yl]methanone
• 化学式: C18H15N2O+
• 分子量: 275.3
• InChiKey: GIWBRJFIWLSWOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  33.8
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] COMPOUNDS AND METHODS FOR TARGETING LEUKEMIC STEM CELLS<br/>[FR] COMPOSÉS ET PROCÉDÉS DE CIBLAGE DE CELLULES SOUCHES LEUCÉMIQUES
  申请人：BROAD INST INC

  公开号：WO2012112956A2

  公开（公告）日：2012-08-23

  This invention relates to high-throughput, semi-automated methods for identifying compounds that are effective in targeting leukemia stem cells, as well as compounds identified by those methods and uses thereof for treating leukemia.
• [EN] HIGH-THROUGHPUT ASSAYS TO PROBE LEUKEMIA WITHIN THE STROMAL NICHE<br/>[FR] DOSAGES À GRAND RENDEMENT DESTINÉS À DÉTECTER LA LEUCÉMIE DANS LA NICHE STROMALE
  申请人：BROAD INST INC

  公开号：WO2012112958A2

  公开（公告）日：2012-08-23

  This invention relates to high-throughput, semi-automated methods for identifying compounds that are effective in targeting leukemia stem cells, as well as compounds identified by those methods and uses thereof for treating leukemia.