4H-1-Benzopyran-4-one, 2-(2,5-dimethoxyphenyl)-5,7-dihydroxy- | 89971-02-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 4H-1-Benzopyran-4-one, 2-(2,5-dimethoxyphenyl)-5,7-dihydroxy-
• 英文别名: 2-(2,5-dimethoxyphenyl)-5,7-dihydroxychromen-4-one
• CAS: 89971-02-8
• 化学式: C₁₇H₁₄O₆
• 分子量: 314.295
• InChiKey: QQYUQGPNZPVDTK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  5,7,2'-trihydroxy-5'-methoxyflavone 、 三甲基硅烷化重氮甲烷 以 甲醇 、 正己烷 为溶剂， 以7 mg的产率得到5-hydroxy-7,2',5'-trimethoxyflavone
  参考文献：
  名称：

  A new antioxidant flavonoid from the lianas ofGnetum macrostachyum

  摘要：

  A new flavonoid, named 5,7,2'-trihydroxy-5'-methoxyflavone (1), was isolated from the acetone extract of the lianas of Gnetum macrostachyum together with 5,7,4'-trihydroxy-3'-methoxyflavanone (2) and seven known stilbenoids (3-7). The structure of the new compound was determined by interpretation of its spectral data and chemical transformation. The isolated compounds showed radical scavenging activity against DPPH with IC50 values in the range of 0.21-19.90mM.

  DOI：

  10.1080/14786410802280943

文献信息

• A new antioxidant flavonoid from the lianas of<i>Gnetum macrostachyum</i>
  作者：Suwannee Saisin、Santi Tip-pyang、Preecha Phuwapraisirisan

  DOI：10.1080/14786410802280943

  日期：2009.11.10

  A new flavonoid, named 5,7,2'-trihydroxy-5'-methoxyflavone (1), was isolated from the acetone extract of the lianas of Gnetum macrostachyum together with 5,7,4'-trihydroxy-3'-methoxyflavanone (2) and seven known stilbenoids (3-7). The structure of the new compound was determined by interpretation of its spectral data and chemical transformation. The isolated compounds showed radical scavenging activity against DPPH with IC50 values in the range of 0.21-19.90mM.