2-[2-[2-[2-(Trifluoromethylsulfonyloxy)ethoxy]ethoxy]ethoxy]ethyl trifluoromethanesulfonate | 201665-20-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 2-[2-[2-[2-(Trifluoromethylsulfonyloxy)ethoxy]ethoxy]ethoxy]ethyl trifluoromethanesulfonate
• CAS: 201665-20-5
• 化学式: C₁₀H₁₆F₆O₉S₂
• 分子量: 458.354
• InChiKey: IGSXEAFKAQFAPU-UHFFFAOYSA-N

物化性质

• 沸点：
  413.1±45.0 °C(Predicted)
• 密度：
  1.526±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  27
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  131
• 氢给体数：
  0
• 氢受体数：
  15

反应信息

• 作为反应物：
  描述：

  2-[2-[2-[2-(Trifluoromethylsulfonyloxy)ethoxy]ethoxy]ethoxy]ethyl trifluoromethanesulfonate 在 四(三苯基膦)钯 、 三苯基膦 作用下， 以 四氢呋喃 、 二甲基亚砜 为溶剂， 反应 1.0h， 生成 15-Methylene-5,8,11-trioxa-bicyclo[14.2.2]icosa-1(19),16(20),17-triene
  参考文献：
  名称：

  Synthesis of Polyether Exomethylene Paracyclophanes via an Intramolecular Pd-Catalyzed Bis-Enyne Benzannulation Protocol

  摘要：

  Several novel crownlike exomethylene paracyclophanes were efficiently synthesized via an intramolecular palladium-catalyzed benzannulation of conjugated bis-enynes. A method for the efficient synthesis of bis-enynes 8, bearing an oligo(oxyethylene) linkage, was developed by utilizing a two-step procedure from commercially available and inexpensive ethylene glycols. A remarkable complete reversal of reactivity of ambident dilithiated nucleophile 4 toward triflate 7 in the presence of 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) was found.

  DOI：

  10.1021/jo9717705
• 作为产物：
  描述：

  三缩四乙二醇 、 三氟甲磺酸酐 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 生成 2-[2-[2-[2-(Trifluoromethylsulfonyloxy)ethoxy]ethoxy]ethoxy]ethyl trifluoromethanesulfonate
  参考文献：
  名称：

  Synthesis of Polyether Exomethylene Paracyclophanes via an Intramolecular Pd-Catalyzed Bis-Enyne Benzannulation Protocol

  摘要：

  Several novel crownlike exomethylene paracyclophanes were efficiently synthesized via an intramolecular palladium-catalyzed benzannulation of conjugated bis-enynes. A method for the efficient synthesis of bis-enynes 8, bearing an oligo(oxyethylene) linkage, was developed by utilizing a two-step procedure from commercially available and inexpensive ethylene glycols. A remarkable complete reversal of reactivity of ambident dilithiated nucleophile 4 toward triflate 7 in the presence of 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) was found.

  DOI：

  10.1021/jo9717705

文献信息

• Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers
  申请人：Andrews Allen Mark

  公开号：US20060264672A1

  公开（公告）日：2006-11-23

  Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers are disclosed. The processes can be used to form polymers, particularly crosslinked polymers.

  本发明公开了使用α，ω-双官能团醛胺作为单体和交联剂的过程。该过程可用于形成聚合物，特别是交联聚合物。
• PROCESSES FOR PREPARING POLYMERS USING ALPHA,OMEGA-DIFUNCTIONAL ALDARAMIDES
  申请人：Andrews Mark Allen

  公开号：US20080146768A1

  公开（公告）日：2008-06-19

  Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers are disclosed. The processes can be used to form polymers, particularly crosslinked polymers.

  本发明揭示了使用α，ω-二官能团醛胺作为单体和交联剂的过程。该过程可用于形成聚合物，特别是交联聚合物。
• Synthesis of Polyether Exomethylene Paracyclophanes via an Intramolecular Pd-Catalyzed Bis-Enyne Benzannulation Protocol
  作者：Douglas Weibel、Vladimir Gevorgyan、Yoshinori Yamamoto

  DOI：10.1021/jo9717705

  日期：1998.2.1

  Several novel crownlike exomethylene paracyclophanes were efficiently synthesized via an intramolecular palladium-catalyzed benzannulation of conjugated bis-enynes. A method for the efficient synthesis of bis-enynes 8, bearing an oligo(oxyethylene) linkage, was developed by utilizing a two-step procedure from commercially available and inexpensive ethylene glycols. A remarkable complete reversal of reactivity of ambident dilithiated nucleophile 4 toward triflate 7 in the presence of 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) was found.