(2E,3E)-2,3-bis[amino(methylsulfanyl)methylidene]butanedinitrile

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2E,3E)-2,3-bis[amino(methylsulfanyl)methylidene]butanedinitrile
• 化学式: C₈H₁₀N₄S₂
• 分子量: 226.3
• InChiKey: LBQNBMSPTURKGS-SFECMWDFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  150
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• METHOD FOR THE SELECTION OF COMPOUNDS USEFUL FOR THE TREATMENT OF PSYCHIATRIC AND NEURODEGENERATIVE DISEASES
  申请人：Tongiorgi Enrico

  公开号：US20130224754A1

  公开（公告）日：2013-08-29

  The present invention concerns a method for the identification of specific compounds which modulate brain-derived neurotrophic factor, which can be used as drugs for the treatment of neurological and neuropsychiatric diseases and which are suitable for the treatment of deleterious effects caused to the nervous system by abuse of illegal or legal drugs.
• DIFFERENTIATION OF CORTICAL NEURONS FROM HUMAN PLURIPOTENT STEM CELLS
  申请人：MEMORIAL SLOAN-KETTERING CANCER CENTER

  公开号：US20180346875A1

  公开（公告）日：2018-12-06

  The presently disclosed subject matter provides for in vitro methods of inducing differentiation of human stem cells into cortical neurons, and cortical neurons generated by such methods. The presently disclosed subject matter also provides for uses of such cortical neurons for treating neurodegenerative CNS disorders.
• [EN] DIFFERENTIATION OF CORTICAL NEURONS FROM HUMAN PLURIPOTENT STEM CELLS<br/>[FR] DIFFÉRENCIATION DE NEURONES CORTICAUX À PARTIR DE CELLULES SOUCHES PLURIPOTENTES HUMAINES
  申请人：MEMORIAL SLOAN KETTERING CANCER CENTER

  公开号：WO2017132596A1

  公开（公告）日：2017-08-03

  The presently disclosed subject matter provides for in vitro methods of inducing differentiation of human stem cells into cortical neurons, and cortical neurons generated by such methods. The presently disclosed subject matter also provides for uses of such cortical neurons for treating neurodegenerative CNS disorders.