2-O-methyl-D-xylose | 18652-95-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-O-methyl-D-xylose
• 英文别名: 2-O-Methyl-beta-D-xylopyranose；(2R,3R,4S,5R)-3-methoxyoxane-2,4,5-triol
• CAS: 18652-95-4
• 化学式: C₆H₁₂O₅
• 分子量: 164.158
• InChiKey: UAXFCDNRLADBDZ-JGWLITMVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  protolinckioside A 在 三氟乙酸 作用下， 以 水 为溶剂， 反应 2.0h， 生成 2-O-methyl-D-xylose
  参考文献：
  名称：

  四种新的甾体糖苷 Protolinckiosides A - D，来自 StarfishProtoreaster lincki

  摘要：

  从海星 Protoreaster lincki 的 MeOH/EtOH 提取物中分离出四种新的甾体糖苷，protolinckiosides A – D（分别为 1 – 4 和）以及四种先前已知的糖苷 5 – 8。1-4 的结构通过广泛的 NMR 和 ESI-MS 技术阐明为 (3β,4β,5α,6β,7α,15α,16β,25S)-4,6,7,8,15,16,26-heptahydroxycholestan ‐3-yl 2-O-methyl-β-d-xylopyranoside (1), (3β,5α,6β,15α,24S)-3,5,6,8,15-pentahydroxycholestan-24-yl α-l-阿拉伯呋喃糖苷 (2), 钠 (3β,6β,15α,16β,24R)-29-(β-d-呋喃半乳糖氧基)-6,8,16-三羟基-3-[(2-O-甲基-β-d-吡喃木糖基）氧基]stigmast-4-en-15-yl

  DOI：

  10.1002/cbdv.201500336

文献信息

• (METH)ACRYLATE MANUFACTURING METHOD
  申请人：TOAGOSEI CO., LTD

  公开号：US20180118658A1

  公开（公告）日：2018-05-03

  The present invention provides a (meth)acrylate manufacturing method characterized in that when manufacturing a (meth) acrylate by an ester exchange reaction between an alcohol and a monofunctional (meth)acrylate using catalyst A and catalyst B together, contact treatment of the ester exchange reaction product with adsorbent C is performed. Catalyst A: One or more kinds of compounds selected from a group consisting of cyclic tertiary amines with an azabicyclo structure and salts or complexes thereof, amidine and salts or complexes thereof, compounds with a pyridine ring and salts or complexes thereof, phosphines and salts or complexes thereof, and compounds with a tertiary diamine structure and salts or complexes thereof. Catalyst B: One or more kinds of compounds selected from a group consisting of compounds comprising zinc. Adsorbent C: One or more kinds of compounds selected from a group consisting of oxides and hydroxides comprising at least one of magnesium, aluminum and silicon.

  本发明提供了一种（甲基）丙烯酸酯制备方法，其特征在于通过在使用催化剂A和催化剂B一起进行醇和单官能基（甲基）丙烯酸酯之间的酯交换反应制备（甲基）丙烯酸酯时，对酯交换反应产物进行与吸附剂C的接触处理。催化剂A：从含有氮杂双环结构的环状三级胺及其盐或络合物、胺嘧啶及其盐或络合物、含有吡啶环的化合物及其盐或络合物、膦及其盐或络合物、以及含有三级二胺结构的化合物及其盐或络合物中选择的一种或多种化合物。催化剂B：从含锌化合物中选择的一种或多种化合物。吸附剂C：从含有镁、铝和硅中至少一种的氧化物和氢氧化物中选择的一种或多种化合物。
• MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD
  申请人：TOAGOSEI CO., LTD.

  公开号：US20170204044A1

  公开（公告）日：2017-07-20

  [Problem] The purpose of the present invention is to obtain a multifunctional (meth)acrylate with good yield by an ester exchange reaction of a polyhydric alcohol such as pentaerythritol or dipentaerythritol with a monofunctional (meth)acrylate. [Solution] A multifunctional (meth)acrylate manufacturing method characterized in that when manufacturing a multifunctional (meth)acrylate by an ester exchange reaction of a polyhydric alcohol with a monofunctional (meth)acrylate, catalyst (A) and catalyst (B) are used together. Catalyst (A): One or more kinds of compounds selected from a group consisting of cyclic tertiary amines with an azabicyclo structure or salts or complexes thereof, amidines or salts or complexes thereof, and compounds with a pyridine ring or salts or complexes thereof. Catalyst (B): One or more kinds of compounds selected from a group consisting of zinc-containing compounds.

  [问题] 本发明的目的是通过多元醇（如戊三醇或二戊三醇）与单官能基（甲基）丙烯酸酯的酯交换反应，获得产率高的多功能（甲基）丙烯酸酯。[解决方案] 一种多功能（甲基）丙烯酸酯制备方法，其特征在于，在通过多元醇与单官能基（甲基）丙烯酸酯的酯交换反应制备多功能（甲基）丙烯酸酯时，同时使用催化剂（A）和催化剂（B）。催化剂（A）：选自具有氮杂双环结构的环三胺或其盐或络合物、酰胺或其盐或络合物以及吡啶环或其盐或络合物组成的群中的一种或多种化合物。催化剂（B）：选自含锌化合物组成的群中的一种或多种化合物。
• METHOD FOR PRODUCING (METH)ACRYLATE
  申请人：TOAGOSEI CO., LTD.

  公开号：US20180105483A1

  公开（公告）日：2018-04-19

  A method for producing a (meth) acrylate comprises transesterification reaction of an alcohol and a monofunctional (meth) acrylate with catalysts in combination being cyclic tertiary amines having an azabicyclo structure and compounds containing zinc, separating a solid that contains the catalysts from a reaction product containing a (meth) acrylate, and producing a (meth) acrylate by transesterification reaction of an alcohol and a monofunctional (meth) acrylate, while using the recovered solid catalyst.

  生产（甲基）丙烯酸酯的方法包括使用具有氮杂双环结构的环状三级胺和含锌化合物作为催化剂，将醇和单官能团（甲基）丙烯酸酯进行酯交换反应，从含有催化剂的固体中分离出含有（甲基）丙烯酸酯的反应产物，然后通过将醇和单官能团（甲基）丙烯酸酯进行酯交换反应，并使用回收的固体催化剂来生产（甲基）丙烯酸酯。
• SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF EYE DISEASE
  申请人：Daiichi Sankyo Company, Limited

  公开号：US20170260228A1

  公开（公告）日：2017-09-14

  The present invention relates to a terpenoid derivative that has the ability to activate the Keap1/Nrf2/ARE signaling pathway and is excellent in anti-inflammatory action and cytoprotective action, and a sustained-release pharmaceutical composition effective for the treatment and prevention of a posterior eye disease caused by oxidative stress, comprising the terpenoid derivative as an active ingredient. The present invention provides a local administration-type sustained-release pharmaceutical composition for the treatment or prevention of a posterior eye disease, comprising the terpenoid derivative of the present invention as an active ingredient, wherein the sustained-release pharmaceutical composition maintains a pharmacological action thereof for 1 week or longer by the sustained release of the terpenoid derivative under physiological conditions and has a base material administrable to the vitreous body and a form administrable to the vitreous body.

  本发明涉及一种萜类衍生物，具有激活Keap1/Nrf2/ARE信号通路的能力，在抗炎作用和细胞保护作用方面表现出色，并且是一种持续释放的药物组合物，对由氧化应激引起的后眼部疾病的治疗和预防具有有效性，包括萜类衍生物作为活性成分。本发明提供了一种局部给药型持续释放的药物组合物，用于治疗或预防后眼部疾病，包括本发明的萜类衍生物作为活性成分，其中该持续释放的药物组合物通过在生理条件下持续释放萜类衍生物，能够在1周或更长时间内保持其药理作用，并且具有可用于玻璃体的基质和可用于玻璃体的形式。
• NOVEL MICROORGANISM, AND PLANT DISEASE CONTROL AGENT USING THE MICROORGANISM
  申请人：University of Yamanashi

  公开号：EP2311936A1

  公开（公告）日：2011-04-20

  A novel microorganism which can be expected to have both a preventive effect and a therapeutic effect and may be applied to various phytopathogenic bacteria, and whose effects are not reduced even when used in combination with a chemical pesticide, and a plant disease control agent using the microorganism are provided. A Bacillus subtilis strain KS1 (NITE BP-569) which is a novel microorganism and a plant disease control agent including the culture and/or the microorganism bacterial cell of the microorganism as an active ingredient are provided.

  本发明提供了一种可望同时具有预防效果和治疗效果并可用于各种植物病原菌、即使与化学农药结合使用其效果也不会降低的新型微生物，以及一种使用该微生物的植物病害控制剂。 提供了一种枯草芽孢杆菌菌株 KS1（NITE BP-569），它是一种新型微生物，还提供了一种植物病害防治剂，其中包括作为有效成分的该微生物的培养物和/或微生物细菌细胞。