5-Oxohex-2-ynyl acetate | 606489-57-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5-Oxohex-2-ynyl acetate
• CAS: 606489-57-0
• 化学式: C₈H₁₀O₃
• 分子量: 154.166
• InChiKey: AKLQSQDCXXROST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(2-propenoxy)-3-methyl-2-butene 、 5-Oxohex-2-ynyl acetate 在 Hoveyda-Grubbs catalyst second generation 、 对苯醌 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 0.5h， 生成
  参考文献：
  名称：

  Geminal Alkene–Alkyne Cross Metathesis Using a Relay Strategy

  摘要：

  A relay strategy was employed to achieve an intermolecular ene-yne metathesis between 1,1-disubstituted alkenes and alkynes. The relay serves to activate an unreactive alkene which will not participate in ene-yne metathesis. The new relay cross ene-yne metathesis gives rise to 1,1,3-trisubstituted-1,3-dienes previously inaccessible by direct ene-yne metathesis methods.

  DOI：

  10.1021/ol301846q

文献信息

• Geminal Alkene–Alkyne Cross Metathesis Using a Relay Strategy
  作者：Joseph R. Clark、Jonathan M. French、Edgars Jecs、Steven T. Diver

  DOI：10.1021/ol301846q

  日期：2012.8.17

  A relay strategy was employed to achieve an intermolecular ene-yne metathesis between 1,1-disubstituted alkenes and alkynes. The relay serves to activate an unreactive alkene which will not participate in ene-yne metathesis. The new relay cross ene-yne metathesis gives rise to 1,1,3-trisubstituted-1,3-dienes previously inaccessible by direct ene-yne metathesis methods.