5-氰基-2,3-二(4-甲基苯基)四唑氯化物 | 90217-02-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 中文名称: 5-氰基-2,3-二(4-甲基苯基)四唑氯化物
• 中文别名: 5-氰基-2,3-二-(p-苄基-四唑氯化物
• 英文名称: 5-Cyano-2,3-di-p-tolyltetrazolium chloride
• 英文别名: 2,3-bis(4-methylphenyl)tetrazol-2-ium-5-carbonitrile;chloride
• CAS: 90217-02-0
• 化学式: C16H14ClN5
• 分子量: 311.77
• InChiKey: SSJZAXOTLCJNLF-UHFFFAOYSA-M

物化性质

• 熔点：
  225 ℃
• 溶解度：
  溶于水
• 最大波长(λmax)：
  450nm (of formazan)
• 稳定性/保质期：

  按规定使用和贮存的该物质不会分解，应避免接触氧化物、光线。

计算性质

• 辛醇/水分配系数(LogP)：
  -0.96
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  58.4
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26
• 危险类别码：
  R36/37/38

文献信息

• Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens
  申请人：Singleton Fain Scott

  公开号：US20060199768A1

  公开（公告）日：2006-09-07

  Compounds for modulating RecA protein activity are provided. In some embodiments, the compounds modulate RecA activity by interfering with assembly of monomeric RecA protein subunits into a nucleoprotein filament. In some embodiments, the compounds modulate RecA activity by interfering with adenosine triphosphate hydrolysis by the RecA protein. Methods of screening for and methods of using the compounds are also provided.

  提供了用于调节RecA蛋白活性的化合物。在某些实施例中，这些化合物通过干扰单体RecA蛋白亚基的组装成为核蛋白丝来调节RecA活性。在某些实施例中，这些化合物通过干扰RecA蛋白的三磷酸腺苷水解来调节RecA活性。还提供了筛选这些化合物的方法和使用这些化合物的方法。
• Chemical probe compounds that become fluorescent upon reduction, and methods for their use
  申请人：Cheung Ching-Ying

  公开号：US20060199242A1

  公开（公告）日：2006-09-07

  Chemical stain compounds containing a fluorophore and a reducible quenching unit are disclosed. The reducible quenching unit quenches the fluorophore while in its oxidized state. Upon reduction, the quenching properties of the quenching unit are diminished or eliminated. The chemical compounds can be used in a variety of applications, including the detection of bacterial cells, monitoring the electron transport chain function of bacterial cells, monitoring the oxidation state of non-biological systems, and assaying the effectiveness of antibacterial or antimicrobial agents.

  本发明涉及一种化学染料化合物，其含有荧光团和可还原的猝灭单元。可还原的猝灭单元在氧化状态下猝灭荧光团。在还原后，猝灭单元的猝灭性质被减弱或消失。这些化学化合物可以用于各种应用，包括检测细菌细胞、监测细菌细胞的电子传递链功能、监测非生物系统的氧化状态以及测试抗菌或抗微生物药物的有效性。
• CHEMICAL PROBE COMPOUNDS THAT BECOME FLUORESCENT UPON REDUCTION, AND METHODS FOR THEIR USE
  申请人：Cheung Ching-Ying

  公开号：US20080254501A1

  公开（公告）日：2008-10-16

  Chemical stain compounds containing a fluorophore and a reducible quenching unit are disclosed. The reducible quenching unit quenches the fluorophore while in its oxidized state. Upon reduction, the quenching properties of the quenching unit are diminished or eliminated. The chemical compounds can be used in a variety of applications, including the detection of bacterial cells, monitoring the electron transport chain function of bacterial cells, monitoring the oxidation state of non-biological systems, and assaying the effectiveness of antibacterial or antimicrobial agents.

  本发明揭示了一种含有荧光物和可还原淬灭单元的化学染料化合物。可还原淬灭单元在氧化状态下淬灭荧光物。一旦还原，淬灭单元的淬灭性质会减弱或消失。这些化学化合物可以用于多种应用，包括检测细菌细胞，监测细菌细胞的电子传递链功能，监测非生物系统的氧化状态以及评估抗菌或抗微生物药剂的有效性。
• ANTIMICROBIAL COMPOSITIONS
  申请人：Chisholm Bret Ja

  公开号：US20110195041A1

  公开（公告）日：2011-08-11

  Provided are antimicrobial compositions including at least one biocide covalently bound to a polyurethane. The biocide moiety may comprise triclosan, a triclosan derivative, or a quaternary ammonium salt. Further provided are methods of reducing biofilm formation or microbial growth on a surface, the method including applying to the surface an antimicrobial composition including at least one biocide covalently attached to a polyurethane.

  提供了抗微生物组合物，其中至少包括一种生物杀灭剂共价结合到聚氨酯上。生物杀灭剂部分可以包括三氯生、三氯生衍生物或季铵盐。此外，还提供了一种减少生物膜形成或表面微生物生长的方法，该方法包括将至少一种生物杀灭剂共价连接到聚氨酯的抗微生物组合物涂布到表面。
• METHOD FOR SPECIFICALLY LABELING LIVING BACTERIA
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

  公开号：US20140363817A1

  公开（公告）日：2014-12-11

  The present invention concerns a method for labeling specifically living bacteria of a given category in a sample, the method including: a) incubating said bacteria of said sample with at least one analog of a monosaccharide compound, and b) contacting the bacteria with a labeling molecule having a second reactive group.

  本发明涉及一种用于在样品中特异性标记给定类别的活菌的方法，该方法包括：a）将所述样品中的所述菌株与至少一种单糖化合物的类似物一起孵育，并b）将该菌株与具有第二反应性基团的标记分子接触。