Agn-PC-0LP1QD | 7227-22-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Agn-PC-0LP1QD
• 英文别名: 5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,49-tridecol
• CAS: 7227-22-7
• 化学式: C₄₂H₇₀O₃₄
• 分子量: 1119.0
• InChiKey: ADMHCAPIDLNHJS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -14
• 重原子数：
  76
• 可旋转键数：
  7
• 环数：
  21.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  534
• 氢给体数：
  20
• 氢受体数：
  34

文献信息

• MICROSPHERES CONTAINING THERAPEUTIC AGENTS AND RELATED METHODS OF USE
  申请人：Biosphere Medical, Inc.

  公开号：US20170231915A1

  公开（公告）日：2017-08-17

  Microspheres, compositions including the microspheres, and methods of using the microspheres are disclosed herein. The microspheres can be substantially spherical and can include a copolymer of a monomer (such as an acrylic monomer) and a cyclodextrin or a derivative thereof. The microspheres can also include a therapeutic agent, such as a platinum-based drug.

  本文公开了微球、包括微球的组合物以及使用微球的方法。这些微球可以是基本球形的，可以包括单体的共聚物（如丙烯酸单体）和环糊精或其衍生物。这些微球还可以包括治疗剂，如基于铂的药物。
• CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY
  申请人：Davis Mark E.

  公开号：US20110282047A1

  公开（公告）日：2011-11-17

  Described herein is a cyclodextrin containing polymer conjugate.

  这里描述了一种含有环糊精的聚合物共轭物。
• CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
  申请人：Crawford Thomas C.

  公开号：US20120058971A1

  公开（公告）日：2012-03-08

  Methods and compositions relating to CDP-taxane conjugates are described herein.

  本文描述了与CDP-紫杉醇结合物有关的方法和组合物。
• TREATMENT OF CANCER
  申请人：Ryan John

  公开号：US20160058875A1

  公开（公告）日：2016-03-03

  Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.

  提供了涉及包含CDP-拓扑异构酶抑制剂的组合物的方法，例如CDP-喜树碱或喜树碱衍生物结合物，例如CRLX101。
• PROCESS FOR HYDROCRACKING A HYDROCARBON FEED IN THE PRESENCE OF A SULPHIDE CATALYST PREPARED USING A CYCLIC OLIGOSACCHARIDE
  申请人：Diehl Fabrice

  公开号：US20130140215A1

  公开（公告）日：2013-06-06

  Hydrocracking a hydrocarbon feed in the presence of a catalyst comprising an acidic support and an active phase formed from at least one metal from group VIII and at least one metal from group VIB, said catalyst being prepared using a process comprising, in succession: contacting a pre-catalyst comprising said metal from group VIII, said metal from group VIB and said acidic support with a cyclic oligosaccharide of at least 6α-(1,4)-bonded glucopyranose subunits; contacting the acidic support with a solution containing a precursor of metal from group VIII, a precursor of said metal from group VIB and a cyclic oligosaccharide of at least 6α-(1,4)-bonded glucopyranose subunits; and contacting acidic support with a cyclic oligosaccharide of at least 6α-(1,4)-bonded glucopyranose subunits followed by a second contacting acidic solid with a precursor of metal from group VIII and a precursor of metal from group VIB; drying; heat treatment; sulphurization.