2-Formyl-4-methyl-5-carboxy-pyrrol-3-propionsaeure | 5011-08-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-Formyl-4-methyl-5-carboxy-pyrrol-3-propionsaeure
• 英文别名: 2-Formyl-4-methyl-5-carboxy-pyrrol-3-ylpropionsaeure；2-Formyl-4-methyl-5-carboxy-pyrrol-propionsaeure-(3)；5-Carboxy-3-<2-carboxy-ethyl>-2-formyl-4-ethyl-pyrrol；4-Methyl-2-formyl-3-(2-carboxyethyl)-pyrrol-carbonsaeure-(5)；4-(2-carboxy-ethyl)-5-formyl-3-methyl-pyrrole-2-carboxylic acid；3-(5-carboxy-2-formyl-4-methyl-pyrrol-3-yl)-propionic acid；3-(5-Carboxy-2-formyl-4-methyl-pyrrol-3-yl)-propionsaeure；5-Formyl-3-methyl-4-(2-carboxy-ethyl)pyrrole-2-carboxylic acid；4-(2-carboxyethyl)-5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid
• CAS: 5011-08-5
• 化学式: C₁₀H₁₁NO₅
• 分子量: 225.201
• InChiKey: IKMOQVJDKFAXFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  108
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-Formyl-4-methyl-5-carboxy-pyrrol-3-propionsaeure 在 丁二酸 、 水 、 氢溴酸 、 溶剂黄146 作用下， 生成 3-(7,12-diethyl-3,8,13,18-tetramethyl-porphyrin-2-yl)-propionic acid
  参考文献：
  名称：

  Fischer; Berg, Justus Liebigs Annalen der Chemie, 1930, vol. 482, p. 189,202

  摘要：

  DOI：
• 作为产物：
  描述：

  1H-吡咯-3-丙酸,5-(乙酯基)-2-甲酰基-4-甲基- 在 氢氧化钾 作用下， 生成 2-Formyl-4-methyl-5-carboxy-pyrrol-3-propionsaeure
  参考文献：
  名称：

  Fischer; Andersag, Justus Liebigs Annalen der Chemie, 1927, vol. 458, p. 117,147

  摘要：

  DOI：

文献信息

• Cytodeuteroporphyrin^1,2
  作者：G. S. Marks、D. K. Dougall、E. Bullock、S. F. MacDonald

  DOI：10.1021/ja01497a049

  日期：1960.6
• Fischer et al., Justus Liebigs Annalen der Chemie, 1928, vol. 466, p. 147,174
  作者：Fischer et al.

  DOI：——

  日期：——
• The Activation of Aging Stereotypes in Younger and Older Adults
  作者：A. L. Chasteen、N. Schwarz、D. C. Park

  DOI：10.1093/geronb/57.6.p540

  日期：2002.11.1

  The activation of ageism and aging stereotypes in younger and older adults was investigated by manipulating both the valence and the stereotypicality of trait stimuli. Participants completed a lexical decision task in which the stimulus onset asynchronies (SOAs) between the prime and target stimuli were varied to examine the effects of automatic and controlled processing (300 and 2,000 ms, respectively). Both younger and older adults demonstrated strong stereotype activation for elderly stereotypes but relatively weak activation for young stereotypes. Both younger and older adults also demonstrated a positive bias toward older people, which was not moderated by SOA. These findings suggest that younger and older adults do not differ in their accessibility to aging stereotypes or to their age-based biases, which appear to be positive toward elderly people.
• Fischer et al., Justus Liebigs Annalen der Chemie, 1932, vol. 500, p. 137,182
  作者：Fischer et al.

  DOI：——

  日期：——
• Siedel; Grams, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1940, vol. 267, p. 49,57,59
  作者：Siedel、Grams

  DOI：——

  日期：——