胡萝卜毒素 | 14445-65-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 胡萝卜毒素
• 英文名称: heptadeca-1,10t-diene-5,7-diyn-3-ol
• 英文别名: 1,10-Heptadecadiene-5,7-diyn-3-OL, (E)-；(10E)-heptadeca-1,10-dien-5,7-diyn-3-ol
• CAS: 14445-65-9
• 化学式: C₁₇H₂₄O
• 分子量: 244.377
• InChiKey: FXXPOEXJAUWMMJ-MDZDMXLPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  胡萝卜毒素 在 platinum on activated charcoal 氢气 作用下， 以 乙醇 、 苯 为溶剂， 生成 3-heptadecanol
  参考文献：
  名称：

  胡萝卜素的天然毒素-胡萝卜素的结构

  摘要：

  的物质已经从公共胡萝卜，的提取物中分离胡萝卜，这是有毒的生物测定生物体水蚤和小鼠。物理和化学证据表明，这种化合物称为胡萝卜素，是反式-1,10-十七碳二烯-5,7-二炔-3-醇（III）。

  DOI：

  10.1016/s0040-4020(01)83330-5

文献信息

• LOW CALORIE, NON-GRAIN, VEGAN TREATS FOR COMPANION ANIMALS
  申请人：AKAMATSU John William

  公开号：US20120309855A1

  公开（公告）日：2012-12-06

  The invention provides methods of using hay, vegetable and/or fruit pulp, and a hydrocolloid for making animal food; and the food products produced using such methods; and the products then being dried through low-temperature dehydration. The animal food products are free of gluten, grains, legumes, nuts, animal-products, sweeteners, and fats.
• US9023409B2
  申请人：——

  公开号：US9023409B2

  公开（公告）日：2015-05-05
• [EN] COMBINING SERMS, SARMS, AND CANNABINOIDS FOR IMPROVING SAFETY AND EFFICACY OF ENDOCRINE THERAPIES<br/>[FR] COMBINAISON DE SERM, DE SARM ET DE CANNABINOÏDES DESTINÉE À AMÉLIORER LA SÉCURITÉ ET L'EFFICACITÉ D'ENDOCRINOTHÉRAPIES
  申请人：TESS VENTURES INC

  公开号：WO2020160452A1

  公开（公告）日：2020-08-06

  The present invention provides methods for the alleviation of symptoms of diseases or medical conditions impacted by dysfunction of the endocannabinoid system in a subject, the methods comprising administering an effective amount of a SERM, SARM, or other endocrine agent in combination with an effective amount of a cannabinoid or cannabimimetic agent or combination of such agents tailored to a subject's specific symptoms. In particular embodiments, the cannabinoid or cannabimimetic agent or combination of such agents alleviate chemotherapy-induced nausea and vomiting in a subject, while a prescription SERM treats the immuno-suppression associated with cannabinoid-based therapy. In some embodiments, the side effects associated with endocrine therapies in a subject are prevented or limited by administering cannabinoid or cannabimimetic agents or combinations of such agents to the subject. In other embodiments, the side effects associated with cannabinoid or cannabimimetic-based therapies in a subject are prevented or limited by administering a prescription endocrine therapy to the subject.
• The structure of carotatoxin, a natural toxicant from carrot
  作者：D.G. Crosby、N. Aharonson

  DOI：10.1016/s0040-4020(01)83330-5

  日期：1967.1

  A substance has been isolated from extracts of the common carrot, Daucus carota, which is toxic to the bioassay organism Daphnia magna and to mice. Physical and chemical evidence showed this compound, termed carotatoxin, to be trans-1,10-heptadecadiene-5,7-diyn-3-ol (III).

  的物质已经从公共胡萝卜，的提取物中分离胡萝卜，这是有毒的生物测定生物体水蚤和小鼠。物理和化学证据表明，这种化合物称为胡萝卜素，是反式-1,10-十七碳二烯-5,7-二炔-3-醇（III）。