(2R,3R,4S,5S,6S)-2-heptoxy-6-(hydroxymethyl)-4-sulfanyloxane-3,5-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3R,4S,5S,6S)-2-heptoxy-6-(hydroxymethyl)-4-sulfanyloxane-3,5-diol
• 化学式: C₁₃H₂₆O₅S
• 分子量: 294.41
• InChiKey: NPIOYGLETFIKIE-PJSNJIKXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.2
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• METHODS FOR MULTIPLEX ANALYTICAL MEASUREMENTS IN SINGLE CELLS OF SOLID TISSUES
  申请人：PRESIDENT AND FELLOWS OF HARVARD COLLEGE

  公开号：US20150246335A1

  公开（公告）日：2015-09-03

  The invention provides a method for the isolation of a single cell embedded in a tissue while preserving the state of molecules of the cell, and therefore allows for transformation of a single target cell in live tissue into a format that can be evaluated using analytical methods.
• [EN] IRON CHELATORS AND USE THEREOF FOR REDUCING TRANSPLANT FAILURE<br/>[FR] CHÉLATEURS DU FER ET LEUR UTILISATION POUR LA RÉDUCTION D'ÉCHEC DE TRANSPLANTATION
  申请人：UNIV LELAND STANFORD JUNIOR

  公开号：WO2014036414A2

  公开（公告）日：2014-03-06

  Formulations and methods are provided for improving the function, i.e. clinical outcome, of solid organ transplants. Lung transplantation is of particular interest. In the methods of the invention, a nanoparticle formulation comprising an effective dose of an iron chelator active agent in nanoparticle form, including without limitation, deferoxamine (DFO), deferasirox (DFX), and deferiprone (DFP), etc. suspended in a carrier compatible with the tissue of interest, is topically applied to the surface of tissues at the site of anastomosis. The nanoparticles are comprised of the active agent and a pharmaceutically acceptable stabilizer.