1-Pentoxyethenamine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Pentoxyethenamine
• 英文别名: 1-pentoxyethenamine
• 化学式: C₇H₁₅NO
• 分子量: 129.2
• InChiKey: ZBFALAJAIDFMBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• AMINOETHYLATION PROCESS HAVING IMPROVED YIELD OF ARYLOXYALKYLENE AMINE COMPOUNDS AND REDUCED UREA BY-PRODUCTS
  申请人：McDougall Patrick J.

  公开号：US20140073814A1

  公开（公告）日：2014-03-13

  Disclosed is a process for preparing an aryloxyalkylene amine compound via an aminoethylation reaction comprising: a) reacting an aromatic hydroxyl compound in the presence of a basic catalyst with a 2-oxazolidinone compound of the formula II to form an intermediate reaction product; wherein R 3 is selected from the group consisting of hydrogen or lower alkyl having 1 to 6 carbon atoms, R 4 is selected from the group consisting of hydrogen, straight or branched chain alkyl having from one to six carbon atoms, phenyl, alkaryl, or arylalkyl; and b) reacting the intermediate product of step a) with a polyalkylene polyamine.

  揭示了一种通过氨基乙基化反应制备芳基氧基烷胺化合物的过程，包括：a)在碱性催化剂存在下，将芳香羟基化合物与式II的2-噁唑烷酮化合物反应，形成中间反应产物；其中R3选自氢或1至6个碳原子的较低烷基，R4选自氢、一元或分支链烷基（含1至6个碳原子）、苯基、烷基芳基或芳基烷基；b)将步骤a）中间产物与聚烷基聚胺反应。
• AMINOETHYLATION PROCESS FOR PRODUCING ARYLOXYALKYLENE AMINE COMPOUNDS
  申请人：Chevron Oronite Company LLC

  公开号：EP2895456A1

  公开（公告）日：2015-07-22
• PRODRUG COMPOSITIONS
  申请人：The University of Liverpool

  公开号：US20200040015A1

  公开（公告）日：2020-02-06

  The present invention provides a composition comprising nanoparticles of prodrugs of certain pharmaceutically active agents, wherein the nanoparticles of prodrugs are dispersed within a carrier material. The present invention further provides processes for the making of the same.
• US9035097B2
  申请人：——

  公开号：US9035097B2

  公开（公告）日：2015-05-19
• [EN] AMINOETHYLATION PROCESS FOR PRODUCING ARYLOXYALKYLENE AMINE COMPOUNDS<br/>[FR] PROCÉDÉ D'AMINOÉTHYLATION POUR LA PRODUCTION DE COMPOSÉS ARYLOXYALKYLÈNE AMINE
  申请人：CHEVRON ORONITE CO

  公开号：WO2014042756A1

  公开（公告）日：2014-03-20

  Disclosed is a process for preparing an aryloxyalkyiene amine compound via an aminoethylation reaction comprising: a) reacting an aromatic hydroxyl compound in the presence of a basic catalyst with a 2-oxazolidinone compound of the formula II to form an intermediate reaction product; and b) reacting the intermediate product of step a) with a polyalkylene polyamine.