4-(But-2-enyl-1-oxy)-benzaldehyd | 42053-93-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-(But-2-enyl-1-oxy)-benzaldehyd
• 英文别名: 4-(2-butenyloxy)benzaldehyde；4-But-2-enoxybenzaldehyde
• CAS: 42053-93-0
• 化学式: C₁₁H₁₂O₂
• 分子量: 176.215
• InChiKey: GJTUFKFMBKCFIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2912499000

反应信息

• 作为反应物：
  描述：

  4-(But-2-enyl-1-oxy)-benzaldehyd 在 N-溴代丁二酰亚胺(NBS) 、 水 、 potassium carbonate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 0.75h， 生成 C₁₁H₁₂O₃ 、 C₁₁H₁₂O₃
  参考文献：
  名称：

  高度区域选择性和化学选择性的钛茂介导的Barbier型烯丙基化反应。

  摘要：

  钛新世羧酸盐1是出色的化学选择性试剂，可进行前所未有的α-区域选择性Barbier型反应。它构成了第一个能够耐受环氧化物和易于还原的羰基化合物（例如芳族和α，β-不饱和醛）的钛茂（III）。

  DOI：

  10.1039/c3cc49230c
• 作为产物：
  描述：

  N-benzoyl-2-aminoethyl β-D-glucopyranoside 、 4-(4-chlorobutoxy)benzaldehyde 在 sodium hydride 、 甲醇 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.5h， 生成 、 N-(2-(((2R,3R,4S,5S,6R)-3-(4-(4-formylphenoxy)butoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)ethyl)benzamide 、 N-(2-(((2R,3R,4S,5S,6R)-6-((4-(4-formylphenoxy)butoxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)ethyl)benzamide 、 4-(But-2-enyl-1-oxy)-benzaldehyd
  参考文献：
  名称：

  Nanostructured styrenic co-polymers containing glucopyranosyl residues and their functionalization

  摘要：

  Sugar-based co-polymers with saccharidic units in stable cyclic form and nanometric morphologies stabilized through crosslinking, adaptable through specific functionalizations to biochemical interaction studies with copper-containing amine oxidases, were synthesized from appropriate monomers and macromonomers. The most promising nanospherical co-polymer obtained, containing beta-D-glucopyranosidic units, was employed in functionalization reactions with the help of model molecules, achieving useful transformations mainly at the 6-position and to a minor extent at the 2-position of the saccharidic system. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.05.033

文献信息

• Highly regioselective and chemoselective titanocene mediated Barbier-type allylation reactions
  作者：Sara P. Morcillo、Ángela Martínez-Peragón、Verena Jakoby、Antonio J. Mota、Christian Kube、José Justicia、Juan M. Cuerva、Andreas Gansäuer

  DOI：10.1039/c3cc49230c

  日期：——

  carboxylate 1 is an excellent chemoselective reagent for unprecedented alpha-regioselective Barbier-type reactions. It constitutes the first titanocene(III) able to tolerate epoxides and readily reduced carbonyl compounds, such as aromatic and alpha,beta-unsaturated aldehydes.

  钛新世羧酸盐1是出色的化学选择性试剂，可进行前所未有的α-区域选择性Barbier型反应。它构成了第一个能够耐受环氧化物和易于还原的羰基化合物（例如芳族和α，β-不饱和醛）的钛茂（III）。
• Nanostructured styrenic co-polymers containing glucopyranosyl residues and their functionalization
  作者：Marco Pocci、Silvana Alfei、Francesco Lucchesini、Vincenzo Bertini、Barbara Idini

  DOI：10.1016/j.tet.2009.05.033

  日期：2009.7

  Sugar-based co-polymers with saccharidic units in stable cyclic form and nanometric morphologies stabilized through crosslinking, adaptable through specific functionalizations to biochemical interaction studies with copper-containing amine oxidases, were synthesized from appropriate monomers and macromonomers. The most promising nanospherical co-polymer obtained, containing beta-D-glucopyranosidic units, was employed in functionalization reactions with the help of model molecules, achieving useful transformations mainly at the 6-position and to a minor extent at the 2-position of the saccharidic system. (C) 2009 Elsevier Ltd. All rights reserved.