(4aS,9S)-3-butoxy-4a-hydroxy-9-pyrrolidin-1-yl-3,8,8a,9-tetrahydro-2H-benzo[f][1,2]benzoxazole-4,5-dione

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4aS,9S)-3-butoxy-4a-hydroxy-9-pyrrolidin-1-yl-3,8,8a,9-tetrahydro-2H-benzo[f][1,2]benzoxazole-4,5-dione
• 化学式: C₁₉H₂₆N₂O₅
• 分子量: 362.4
• InChiKey: PSWYANQETUSOOI-ACILQRCOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  88.1
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• [EN] TETRACYCLINE COMPOUNDS<br/>[FR] COMPOSÉS DE TÉTRACYCLINES
  申请人：TETRAPHASE PHARMACEUTICALS INC

  公开号：WO2014036502A2

  公开（公告）日：2014-03-06

  The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I), or a pharmaceutically acceptable salt thereof, and its therapeutic use.