phosphoric acid;[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl] dihydrogen phosphate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: phosphoric acid;[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl] dihydrogen phosphate
• 化学式: C6H16O13P2
• 分子量: 358.13
• InChiKey: UUYHUWHFSVRHOC-RWOHWRPJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.19
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  243
• 氢给体数：
  9
• 氢受体数：
  13

文献信息

• METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS
  申请人：Agios Pharmaceuticals, Inc.

  公开号：EP3064595A1

  公开（公告）日：2016-09-07

  Methods of treating and evaluating subjects having neoactive mutants of IDH (e.g., IDH1 or IDH2).

  治疗和评估IDH（如IDH1或IDH2）新活性突变体受试者的方法。
• CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD
  申请人：Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

  公开号：EP3313994A1

  公开（公告）日：2018-05-02
• PROBIOTIC COMPOSITIONS AND METHODS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED CONDITIONS
  申请人：PROTHERA, Inc.

  公开号：US20140079676A1

  公开（公告）日：2014-03-20

  The present invention provides a method and composition for ameliorating or reducing the symptoms and signs and for the treatment of obesity, diabetes, and related conditions in a mammal in need thereof, said method comprising administering effective amounts of a pharmaceutically acceptable composition comprising a mixture of probiotic microorganisms with distinct but complementary pathways of carbohydrate metabolism, for a time sufficient to ameliorate, reduce or treat at least one sign or symptom of obesity, diabetes or cardiovascular disease. Compositions having the desired properties, and methods for their use in pharmaceutical and nutritional formulations, are provided.
• MICROORGANISM HAVING ENHANCED CELLULOSE PRODUCTIVITY, METHOD OF PRODUCING CELLULOSE BY USING THE SAME, AND METHOD OF PRODUCING THE MICROORGANISM
  申请人：Samsung Electronics Co., Ltd.

  公开号：US20190144904A1

  公开（公告）日：2019-05-16

  Provided are a microorganism having enhanced cellulose productivity, a method of producing cellulose by using the microorganism, and a method of producing the microorganism.
• [EN] CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD<br/>[FR] VOIES DE CONTOURNEMENT DE LA PHOTORESPIRATION NEUTRES ET POSITIVES SUR LE PLAN DU CARBONE PERMETTANT D'OBTENIR UNE VITESSE ET UN RENDEMENT SUPÉRIEURS DE LA PHOTOSYNTHÈSE
  申请人：MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V

  公开号：WO2016207219A1

  公开（公告）日：2016-12-29

  The present invention relates to an organism, a tissue, a cell or an organelle expressing enzymes which allow the conversion of 2-phosphoglycolate (2-PG; also known as glycolate 2-phosphate,) into an intermediate compound of the Calvin-Benson-Bassham Cycle (CBBC) without releasing CO2. The organism, tissue, cell or organelle of the invention may be genetically engineered, transgenic and/or transplastomic so as to express at least one enzyme which is involved in this conversion. The present invention further relates to an organism, tissue, cell or organelle which comprises/expresses at least one enzyme which is involved in this conversion. The present invention further relates to a method for producing an organism, tissue, cell or organelle of the invention. The present invention further relates to a method of enzymatically converting 2-PG into an intermediate compound of the CBBC without releasing CO2. The present invention further relates to the use of an organism, tissue, cell or organelle of the invention for enzymatically converting 2-PG into an intermediate compound of the CBBC without releasing CO2.