(2R,3S,4R,5S)-2,3,4,5-tetrahydroxy-6-methoxy-6-oxohexanoic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4R,5S)-2,3,4,5-tetrahydroxy-6-methoxy-6-oxohexanoic acid
• 化学式: C₇H₁₂O₈
• 分子量: 224.17
• InChiKey: GRRUXFKYWCJHGB-RSJOWCBRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.8
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  145
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• [EN] EGFR-TARGETED NANOPARTICLES<br/>[FR] NANOPARTICULES CIBLANT R-EGF
  申请人：CALIFORNIA INST OF TECHN

  公开号：WO2015157213A1

  公开（公告）日：2015-10-15

  Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled via a boronic ester to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle. EGFR-targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.

  本文描述了一种载体纳米颗粒，其中包含一种聚合物，该聚合物通过硼酯与含硼酸的聚合物偶联，设计为将含硼酸的聚合物呈现给纳米颗粒外部的环境。还描述了所述纳米颗粒的EGFR靶向版本，以及相关的组合物、方法和系统。
• [EN] SYNERGISTIC SELENOPEPTIDE FORMULATIONS FOR THE PROTECTION OF DERMAL PAPILLA CELLS<br/>[FR] FORMULATIONS DE SÉLÉNOPEPTIDE SYNERGIQUES POUR LA PROTECTION DE CELLULES DE PAPILLES DERMIQUES
  申请人：MAJEED MUHAMMED

  公开号：WO2013169273A1

  公开（公告）日：2013-11-14

  The present invention discloses selenium peptide based synergistic compositions for the protection (morphology and viable numbers) of dermal papilla cells. The synergistic compositions disclosed in the present invention comprise (a) 1-O-galloyl-β-D-glucose (β-glucogallin) or 1-O-galloyl-β-D-glucose (β-glucogallin) and gallates (b) concentrate of liquid endosperm of Cocos nucifera and (c) selenopeptides.