3,3,4-Trihydroxycyclohexane-1,2-dione

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,3,4-Trihydroxycyclohexane-1,2-dione
• 英文别名: 3,3,4-trihydroxycyclohexane-1,2-dione
• 化学式: C₆H₈O₅
• 分子量: 160.12
• InChiKey: DEXLBVIJCKFFHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  94.8
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• PHARMACEUTICAL COMPOSITION CONSISTING OF BLAUTIA, FOR ORAL ADMINISTRATION
  申请人：Evelo Biosciences, Inc.

  公开号：EP3747450A1

  公开（公告）日：2020-12-09

  Probiotic compositions containing non-pathogenic microbial entities, e. g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prehiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.

  本文描述了含有非致病性微生物实体（如细菌实体）的益生菌组合物。益生菌组合物可选择性地含有一种或多种预益生菌或与之结合使用。还提供了益生菌组合物治疗或预防受试者局部或全身微生物组紊乱的用途。
• Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
  申请人：Evelo Biosciences, Inc.

  公开号：US10869903B2

  公开（公告）日：2020-12-22

  Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.

  本文描述了含有非致病性微生物实体（如细菌或真菌实体）的益生菌组合物。益生菌组合物可选择含有一种或多种益生元或与之结合使用。还提供了益生菌组合物治疗或预防移植失调的用途，例如移植抗宿主疾病（GVHD）。
• Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome
  申请人：Evelo Biosciences, Inc.

  公开号：US10980845B2

  公开（公告）日：2021-04-20

  Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.

  本文描述了含有非致病性微生物实体（如细菌实体）的益生菌组合物。益生菌组合物可选择含有一种或多种益生元或与之结合使用。还提供了益生菌组合物治疗或预防受试者局部或全身微生物组紊乱的用途。
• PROTEIN MANIPULATION
  申请人：Rebio Technologies Limited

  公开号：EP2852663A1

  公开（公告）日：2015-04-01
• PROBIOTIC AND PREBIOTIC COMPOSITIONS COMPRISING BLAUTIA SPECIES FOR REDUCING INFLAMMATION
  申请人：Evelo Biosciences, Inc.

  公开号：EP3223834B1

  公开（公告）日：2020-05-06