7,18-Bis[2-[bis(pyridin-2-ylmethyl)amino]ethyl]-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(23),2,4,9,11,13,15,20(24),21,25-decaene-6,8,17,19-tetrone | 1150633-21-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 7,18-Bis[2-[bis(pyridin-2-ylmethyl)amino]ethyl]-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(23),2,4,9,11,13,15,20(24),21,25-decaene-6,8,17,19-tetrone
• 英文别名: 7,18-bis[2-[bis(pyridin-2-ylmethyl)amino]ethyl]-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(23),2,4,9,11,13,15,20(24),21,25-decaene-6,8,17,19-tetrone
• CAS: 1150633-21-8
• 化学式: C₅₂H₄₀N₈O₄
• 分子量: 840.941
• InChiKey: PAYAAWQVOIIZAM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  64
• 可旋转键数：
  14
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  133
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  3,4,9,10-苝四羧酸二酐 、 N,N-二(2-吡啶甲基)乙二胺 以 丙醇 、 水 为溶剂， 反应 24.0h， 以53%的产率得到7,18-Bis[2-[bis(pyridin-2-ylmethyl)amino]ethyl]-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(23),2,4,9,11,13,15,20(24),21,25-decaene-6,8,17,19-tetrone
  参考文献：
  名称：

  An “Off-On” Type UTP/UDP Selective Fluorescent Probe and Its Application to Monitor Glycosylation Process

  摘要：

  A New fluorescent sensor based on a peryiene-dpa-Zn platform was synthesized. Selective "Off-On" type fluorescence changes were observed upon the addition of UTP and UDP, which was also applied to monitor glycosylation processes.

  DOI：

  10.1021/ol9004849

文献信息

• A new perylene diimide-based fluorescent chemosensor for selective detection of ATP in aqueous solution
  作者：Liwei Yan、Zhongbin Ye、Chunxiang Peng、Shihong Zhang

  DOI：10.1016/j.tet.2012.01.028

  日期：2012.3

  A new perylene diimide (PDI) ligand (1) functionalized with a Zn2+-dipicolylethylenediamine (Zn2+-DPEN) moiety was synthesized and first used as a fluorometric chemosensor to specifically detect the presence of ATP over other phosphate anions in aqueous solution. The solution of 1 upon addition of ATP displayed a remarkable absorption decrease compared with other anions, indicating the selectivity of 1 to ATP. Moreover, among these anions investigated, only ATP showed a considerable enhancement of fluorescent intensity of 1. The fluorescence molar ratio plot combined with the ESI-TOF mass measurement determined that binding stoichiometry between 1 and ATP is 1:1. (C) 2012 Elsevier Ltd. All rights reserved.