2-Chloro-5-nitro-N-(2-oxo-2-phenylethyl)benzamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Chloro-5-nitro-N-(2-oxo-2-phenylethyl)benzamide
• 英文别名: 2-chloro-5-nitro-N-phenacylbenzamide
• 化学式: C15H11ClN2O4
• 分子量: 318.71
• InChiKey: VTNWCVCGMWERSY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  92
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO
  申请人：Dow AgroSciences LLC

  公开号：US20180098541A1

  公开（公告）日：2018-04-12

  This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

  这份披露涉及具有对节肢动物门、软体动物门和线虫门害虫有用的杀虫性的分子领域，用于生产这种分子的过程，用于这种过程的中间体，含有这种分子的杀虫组合物，以及使用这种杀虫组合物对这些害虫进行处理的过程。这些杀虫组合物可以用作螨虫剂、杀虫剂、螨虫剂、软体动物杀虫剂和线虫杀虫剂。本文件披露了具有以下式（“式一”）的分子。
• [EN] N-(3-HETEROARYLARYL)-4-ARYLARYLCARBOXAMTDES AND ANALOGS AS HEDGEHOG PATHWAY INHIBITORS AND USE THEREOF<br/>[FR] N-(3-HÉTÉROARYLARYL)-4-ARYLARYLCARBOXAMIDES ET ANALOGUES COMME INHIBITEURS DE LA VOIE HEDGEHOG ET LEUR UTILISATION
  申请人：IMPACT THERAPEUTICS INC

  公开号：WO2014012511A1

  公开（公告）日：2014-01-23

  Disclosed are novel N-(3-heteroarylaryl)-4-arylarylcarboxamides and analogs thereof, represented by the Formula I: wherein C cyclic group, D1-D4, Q1, Q2, R5 are defined herein. Compounds having Formula (I) are hedgehog pathway inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of hedgehog activity, such as cancer.

  揭示了一种新颖的N-(3-杂环芳基芳基)-4-芳基芳基羧酰胺及其类似物，表示为公式I：其中C是环状基团，D1-D4，Q1，Q2，R5在此定义。具有公式(I)的化合物是刺猬通路抑制剂。因此，本发明的化合物可用于治疗对刺猬活性抑制敏感的临床病况，如癌症。
• N-(3-heteroarylaryl)-4-arylarylcarboxamides and Analogs as Hedgehog Pathway Inhibitors and Use Thereof
  申请人：IMPACT Therapeutics, Inc.

  公开号：US20150191460A1

  公开（公告）日：2015-07-09

  Disclosed are novel N-(3-heteroarylaryl)-4-arylarylcarboxamides and analogs thereof, represented by the Formula I: wherein C cyclic group, D 1 -D 4 , Q 1 , Q 2 , R 5 are defined herein. Compounds having Formula (I) are hedgehog pathway inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of hedgehog activity, such as cancer.

  揭示了一种新型的N-(3-杂环芳基芳基)-4-芳基芳基羧酰胺及其类似物，其化学式如下：其中C为环状基团，D1-D4，Q1，Q2，R5在此处定义。具有化学式(I)的化合物是刺猬途径抑制剂。因此，本发明的化合物可用于治疗对刺猬活性抑制有响应的临床病况，如癌症。
• MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO
  申请人：Corteva Agriscience LLC

  公开号：EP3971166A1

  公开（公告）日：2022-03-23

  This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula ("Formula One").

  本公开涉及对节肢动物门、软体动物门和线虫动物门害虫具有杀虫作用的分子、生产此类分子的工艺、用于此类工艺的中间体、含有此类分子的杀虫组合物以及使用此类杀虫组合物对付此类害虫的工艺。这些杀虫组合物可用作杀螨剂、杀虫剂、杀螨剂、杀软体动物剂和杀线虫剂等。本文公开了具有下式（"式一"）的分子。
• Molecules having pesticidal utility and intermediates, compositions and processes related thereto
  申请人：Dow AgroSciences LLC

  公开号：US10258045B2

  公开（公告）日：2019-04-16

  This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

  本公开涉及对节肢动物门、软体动物门和线虫动物门害虫具有杀虫作用的分子、生产此类分子的工艺、用于此类工艺的中间体、含有此类分子的杀虫组合物以及使用此类杀虫组合物对付此类害虫的工艺。这些杀虫组合物可用作杀螨剂、杀虫剂、杀螨剂、杀软体动物剂和杀线虫剂等。本文公开了具有下式（"式一"）的分子。