(Z)-1-amino-1-hexadecanoylphosphanyl-1-hydroxynonadec-10-en-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (Z)-1-amino-1-hexadecanoylphosphanyl-1-hydroxynonadec-10-en-2-one
• 化学式: C₃₅H₆₈NO₃P
• 分子量: 581.9
• InChiKey: JHPINMKOZNXZJY-ZCXUNETKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.7
• 重原子数：
  40
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• ANTI-MICROBIAL ACTIVITY OF SYNTHETIC PEPTIDES
  申请人：The United States of American, as represented by the Secretary, Dept. of Health and Human Services

  公开号：US20150322113A1

  公开（公告）日：2015-11-12

  Isolated synthetic peptides are disclosed that have anti-microbial activity against E. coli and P. aeruginosa . These isolated peptides can be used as anti-viral agents. The use of these peptides to treat infections with E. coli and P. aeruginosa and viruses are disclosed. The disclosed peptides are also of use for treating a biofilm, such as a biofilm on a medical device.
• US9243036B2
  申请人：——

  公开号：US9243036B2

  公开（公告）日：2016-01-26
• [EN] ANTI-MICROBIAL ACTIVITY OF SYNTHETIC PEPTIDES<br/>[FR] ACTIVITÉ ANTIMICROBIENNE DE PEPTIDES SYNTHÉTIQUES
  申请人：US HEALTH

  公开号：WO2014028011A1

  公开（公告）日：2014-02-20

  Isolated synthetic peptides are disclosed that have anti-microbial activity against E. coli and P. aeruginosa. These isolated peptides can be used as anti-viral agents. The use of these peptides to treat infections with E. coli and P. aeruginosa and viruses are disclosed. The disclosed peptides are also of use for treating a biofilm, such as a biofilm on a medical device.