(2S,3S,5R)-2-[[(3S,5S)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]methoxymethyl]-6-(hydroxymethyl)oxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3S,5R)-2-[[(3S,5S)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]methoxymethyl]-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₁₄H₂₆O₁₁
• 分子量: 370.35
• InChiKey: IDONTDZDDGYSFP-LILIMBQBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.3
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  190
• 氢给体数：
  8
• 氢受体数：
  11

文献信息

• USE OF LACTULOSE IN THE TREATMENT OF AUTISM
  申请人：Curemark LLC

  公开号：US20160213697A1

  公开（公告）日：2016-07-28

  A treatment for autism in which an effective amount of lactulose is administered in order to bind excess ammonia in the gastrointestinal tract, the bloodstream, and the nervous system in order to prevent or reverse ammonia poisoning caused by the administration of certain antibiotics. Lactulose molecules in the colon are fermented by certain bacteria. The fermentation process lowers the colonic pH, and ammonia, in the form of ammonium ions, is used by the bacteria for amino acid and protein synthesis. This lowers the serum ammonia levels and reduces neurotoxicity.
• US8673877B2
  申请人：——

  公开号：US8673877B2

  公开（公告）日：2014-03-18