4-Amino-5-oxohexanoyl fluoride

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-Amino-5-oxohexanoyl fluoride
• 英文别名: 4-amino-5-oxohexanoyl fluoride
• 化学式: C₆H₁₀FNO₂
• 分子量: 147.15
• InChiKey: NZGSWWFPCDXKFT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  60.2
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DEGENERATIVE DISORDERS<br/>[FR] COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE TROUBLES NEUROLOGIQUES DÉGÉNÉRATIFS
  申请人：KANDULA MAHESH

  公开号：WO2014006528A2

  公开（公告）日：2014-01-09

  The invention relates to the compounds of formula 1 or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof The pharmaceutical compositions comprising an effective amount of compounds of formula I; and methods for treating or preventing neurological degenerative disorders, may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of Alzheimer's disease, Lewy body disease, Huntington's disease, Amyotrophic lateral sclerosis (ALS) and Parkinson's disease.