(2R)-2-amino-1-(1-aminoethenylamino)-4-methylpentan-3-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R)-2-amino-1-(1-aminoethenylamino)-4-methylpentan-3-one
• 化学式: C₈H₁₇N₃O
• 分子量: 171.24
• InChiKey: ISPBWYZYWHAXFE-SSDOTTSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  81.1
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Methods for treatment or prevention of damage resulting from radiation, trauma or shock
  申请人：SYNEDGEN, INC.

  公开号：US10022393B2

  公开（公告）日：2018-07-17

  Described herein are methods of treating a subject that has been or will be exposed to radiation, trauma or shock, the method comprising identifying a subject that has been or will be exposed to radiation, and treating the subject with a compound that treats, reduces the severity or delays the onset of sepsis or reduces the likelihood of mortality in a subject upon administration of a therapeutically effective amount the compound to the subject.

  本文描述的是治疗已经或将要暴露于辐射、创伤或休克的受试者的方法，该方法包括识别已经或将要暴露于辐射的受试者，并用一种化合物治疗受试者，该化合物可在对受试者施用治疗有效量的化合物后治疗、减轻败血症的严重程度或延迟败血症的发生或降低死亡率的可能性。
• METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK
  申请人：SYNEDGEN, INC.

  公开号：US20140080785A1

  公开（公告）日：2014-03-20

  Described herein are methods of treating a subject that has been or will be exposed to radiation, trauma or shock, the method comprising identifying a subject that has been or will be exposed to radiation, and treating the subject with a compound that treats, reduces the severity or delays the onset of sepsis or reduces the likelihood of mortality in a subject upon administration of a therapeutically effective amount the compound to the subject.
• ORAL FORMULATION OF POLYGLUCOSAMINE DERIVATIVES IN COMBINATION WITH A NON-FERMENTABLE SUGAR
  申请人：SYNEDGEN, INC.

  公开号：US20160022564A1

  公开（公告）日：2016-01-28

  Described herein are methods and compositions that contain a soluble polyglucosamine or polyglucosamine derivative for use in oral health. The compositions are useful for, e.g., reducing bacteria (e.g., by clumping and removing) or disrupting a biofilm in the mouth of a subject, reducing dry mouth, and reducing oral inflammation.
• COMPOSITIONS AND METHODS OF USE FOR WOUND HEALING
  申请人：SYNEDGEN INC.

  公开号：US20160022730A1

  公开（公告）日：2016-01-28

  Described herein are a solution, composition, and kit of poly (acetyl, arginyl) glucosamine (PAAG), methods of making the solution, and method of treating wounds with the solution, the method comprising administering to a subject an effective amount of a solution comprising PAAG, wherein the PAAG when administered topically contacts the wound, thereby treating the wound.
• COMPOSITIONS AND METHODS OF USE THEREOF
  申请人：SYNEDGEN, INC.

  公开号：US20170304355A1

  公开（公告）日：2017-10-26

  Described herein are methods for treating or preventing a disease or disorder of the pulmonary system (e.g., cystic fibrosis), respiratory or digestive system in a subject, the methods comprising administering compounds or compositions comprising water soluble polyglucosamine and derivatized polyglucosamine.