2-[(4R)-4-amino-5-oxohexyl]-1,1-dimethylguanidine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[(4R)-4-amino-5-oxohexyl]-1,1-dimethylguanidine
• 化学式: C₉H₂₀N₄O
• 分子量: 200.28
• InChiKey: GGFJWIANRWDTEO-MRVPVSSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  84.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK<br/>[FR] PROCÉDÉS POUR LE TRAITEMENT OU LA PRÉVENTION DE DOMMAGES RÉSULTANT D'UN RAYONNEMENT, D'UN TRAUMA OU D'UN CHOC
  申请人：SYNEDGEN INC

  公开号：WO2014047506A1

  公开（公告）日：2014-03-27

  Described herein are methods of treating a subject that has been or will be exposed to radiation, trauma or shock, the method comprising identifying a subject that has been or will be exposed to radiation, and treating the subject with a compound that treats, reduces the severity or delays the onset of sepsis or reduces the likelihood of mortality in a subject upon administration of a therapeutically effective amount the compound to the subject.