5-[5-(5-Bromothiophen-2-yl)-2-(hydroxymethyl)-6-methylidene-1,2-dihydropyrimidin-3-yl]-2-(hydroxymethyl)oxolan-3-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-[5-(5-Bromothiophen-2-yl)-2-(hydroxymethyl)-6-methylidene-1,2-dihydropyrimidin-3-yl]-2-(hydroxymethyl)oxolan-3-ol
• 英文别名: 5-[5-(5-bromothiophen-2-yl)-2-(hydroxymethyl)-6-methylidene-1,2-dihydropyrimidin-3-yl]-2-(hydroxymethyl)oxolan-3-ol
• 化学式: C₁₅H₁₉BrN₂O₄S
• 分子量: 403.3
• InChiKey: KBRGHHUKCWNLSA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  113
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• [EN] METHOD OF TREATING AND/OR PREVENTING SHINGLES AND METHOD OF TREATING AND/OR PREVENTING ZOSTER ASSOCIATED PAIN<br/>[FR] MÉTHODE DE TRAITEMENT ET/OU DE PRÉVENTION DU ZONA ET MÉTHODE DE TRAITEMENT ET/OU DE PRÉVENTION DE LA DOULEUR ASSOCIÉE AU ZONA
  申请人：EPIPHANY BIOSCIENCES

  公开号：WO2014047562A2

  公开（公告）日：2014-03-27

  Described herein are methods for the treatment and/or prevention of shingles with antiviral agent or salts, solvates or hydrates thereof. Also described herein are methods for the treatment and/or prevention of post herpetic neuralgia with antiviral agents or salts, hydrates or solvates thereof.