6-(2-Hydroxyeth-yl)adenosine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-(2-Hydroxyeth-yl)adenosine
• 英文别名: (2R,3R,4S,5R)-2-[6-amino-6-(2-hydroxyethyl)-8H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
• 化学式: C₁₂H₁₉N₅O₅
• 分子量: 313.31
• InChiKey: BVUGQFOMCBXZCZ-XRDACOTDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  157
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• [EN] NEW CORDYCEPS MILITARIS STRAIN CBS 132098 AND BIOLOGICALLY ACTIVE FRUITING BODIES, MYCELIAL BIOMASS AND EXTRACTS THEREFROM<br/>[FR] NOUVELLE SOUCHE DE CORDYCEPS MILITARIS CBS 132098 ET ORGANES DE FRUCTIFICATION BIOLOGIQUEMENT ACTIFS, BIOMASSE MYCÉLIENNE ET EXTRAITS DE CEUX-CI
  申请人：PHYTO PHARMA PTE LTD

  公开号：WO2014055035A1

  公开（公告）日：2014-04-10

  The invention provides a new and distinct variety of caterpillar medicinal fungus Cordyceps militaris strain CBS 132098 deposited under The Budapest Treaty with the Centralbureau voor Schimmelcultures (CBS) under Accession No. CBS 132098, biomass and extract of this fungus and nutriceutical and pharmaceutical compositions comprising biomass or extract of the fungus.
• [EN] USE OF EXTRACT OR FRACTION OF OPHIOCORDYCEPS IN MANUFACTURE OF MEDICAMENT FOR TREATMENT OF SLEEPING DISORDER<br/>[FR] UTILISATION D'UN EXTRAIT OU D'UNE FRACTION D'OPHIOCORDYCEPS DANS LA FABRICATION D'UN MÉDICAMENT POUR LE TRAITEMENT D'UN TROUBLE DU SOMMEIL
  申请人：MAXGROUP RIGHTS HOLDINGS LTD

  公开号：WO2015092538A1

  公开（公告）日：2015-06-25

  A use of an extract or fraction, derivative or chemically synthesized or modified form of any one or more components of Ophiocordyceps or a genetically modified or phenotypically adapted strain thereof in manufacture of a medicament for treatment a sleeping disorder and the like is provided. A method for treating human subject with a cortisol-based disorder or condition or with the potential for deveploping a cortisol-based disorder or condition is also provided. A system for treating sleep apnea or snoring in a subject is provided comprising an extract or fraction, derivative of Ophiocordyceps or a genetically modified or phenotypically adapted strain thereof or chemically synthesized or modified form of any one or more components.
• [EN] SYSTEM COMPRISING OPHIOCORDYCEPS AND A SLEEP APNEA TREATMENT DEVICE FOR TREATING SLEEP APNEA OR SNORING, METHOD AND USE THEREOF.<br/>[FR] SYSTÈME COMPRENANT DE L'OPHIOCORDYCEPS, ET DISPOSITIF DE TRAITEMENT DE L'APNÉE DU SOMMEIL POUR TRAITER L'APNÉE DU SOMMEIL OU LE RONFLEMENT, PROCÉDÉ ET UTILISATION ASSOCIÉS
  申请人：SLEEPAPP HOLDINGS LTD

  公开号：WO2015092539A1

  公开（公告）日：2015-06-25

  A system comprises an extract or fraction, derivative or chemically synthesized or modified form of any one or more components of Ophiocordyceps or a genetically modified or phenotypically adapted strain thereof, and sleep apnea treatment device. The system acts in synergy to reduce Cortisol levels and increase oxygen saturation, utilization and/or absorption levels. In particularly, the extract is Cs-4 or fraction, derivative or chemically synthesized or modified form of any one or more components. The sleep apnea treatment device comprises a mouthpiece including a vestibular locator and an airway conduit.