5a,10b-dihydro-2,9-dimethyl-4-diphenylphosphinobenzofuro[2,3-b]benzofuran

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5a,10b-dihydro-2,9-dimethyl-4-diphenylphosphinobenzofuro[2,3-b]benzofuran
• 英文别名: [(5aR,10bS)-2,9-dimethyl-5a,10b-dihydro-[1]benzofuro[2,3-b][1]benzofuran-4-yl]-diphenylphosphane
• 化学式: C₂₈H₂₃O₂P
• 分子量: 422.463
• InChiKey: HHJMLUFTGGJVIH-XTEPFMGCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  31
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5a,10b-dihydro-2,9-dimethylbenzofuro[2,3-b]benzofuran 、 二苯基氯化膦 在 N-溴代丁二酰亚胺(NBS) 、 正丁基锂 作用下， 以 N,N-二甲基甲酰胺 、 四氢呋喃 、 正己烷 为溶剂， 反应 74.0h， 以0.23 g的产率得到5a,10b-dihydro-2,9-dimethyl-4-diphenylphosphinobenzofuro[2,3-b]benzofuran
  参考文献：
  名称：

  Large P−P Distance Diphosphines and Their Monophosphine Analogues as Ligands in the Palladium-Catalyzed Telomerization of 1,3-Butadiene and Methanol

  摘要：

  The potential of diphosphines based on a dibenzodioxocin or benzofurobenzofuran backbone possessing large P P distances was studied for the selective telomerization of 1,3-butadiene with methanol under commercially relevant process conditions to obtain 1-methoxyocta-2,7-diene (1-MOD). They were found to act as monophosphines. New bulky monophosphine analogues of the same backbone and ferrocene were also evaluated. Several ligands showed improved selectivity and yield compared to the benchmark ligand PPh3 and monoxantphos. Especially 1,6-bis(diphenylphosphino)-5a,10b-dihydro-5a,10b-dimethyl-3,8-dimethylbenzofuro[3,2-b]benzofuran (3) and, 2,10-di-tert-buty1-4-diphenylphosphino-6,12-methano-12H-dibenzo[2,1-d: 1 ',2"-g][1,3]dioxocin (7), a diphosphine and a monophosphine, respectively, stand out as excellent ligands in terms of yield, selectivity, and stability.

  DOI：

  10.1021/om100980m

文献信息

• A compound comprising ruthenium nanoparticles supported on a porous solid support for the hydrogenation of aromatic compounds.
  申请人：Fundació Institut Català d'Investigació Química

  公开号：EP2719455A1

  公开（公告）日：2014-04-16

  The present invention relates to a process for preparing a catalyst comprising ruthenium nanoparticles supported on a solid support, obtainable by: (a) reacting a ruthenium (0) complex selected from the group consisting of [Ru(diene)(triene)], [Ru(R6)(diene)], and Ru3(CO)12, with a phosphine ligand of formula (I) in the presence of hydrogen; and (b) reacting the ruthenium nanoparticles obtained in Step (a) with a porous solid support, and to the obtained supported phosphine-ruthenium nanoparticles. It is also related to a process for hydrogenating an aromatic compound into the corresponding cyclic saturated or partially unsaturated compound by reaction with hydrogen and in the presence of an effective amount of the obtained supported ruthenium nanoparticles.

  本发明涉及一种制备催化剂的工艺，该催化剂由支撑在固体载体上的纳米钌颗粒组成，可通过以下方法获得：(a) 将选自[Ru(二烯)(三烯)]、[Ru(R6)(二烯)]和 Ru3(CO)12组成的组的钌(0)配合物与式(I)的膦配体在氢存在下反应；以及 (b) 将步骤(a)中得到的钌纳米颗粒与多孔固体载体反应，并与得到的载体膦-钌纳米颗粒反应。本发明还涉及一种通过与氢反应并在有效量的所获得的支撑钌纳米粒子存在下将芳香族化合物氢化为相应的环状饱和或部分不饱和化合物的工艺。
• [EN] A COMPOUND COMPRISING RUTHENIUM NANOPARTICLES SUPPORTED ON A POROUS SOLID SUPPORT FOR THE HYDROGENATION OF AROMATIC COMPOUNDS.<br/>[FR] COMPOSÉ COMPRENANT DES NANOPARTICULES DE RUTHÉNIUM SUPPORTÉES SUR UN SUPPORT SOLIDE POREUX POUR L'HYDROGÉNATION DES COMPOSÉS AROMATIQUES
  申请人：FUNDACIÓ INST CATAL D INVESTIGACIÓ QUÍMICA ICIQ

  公开号：WO2014056889A1

  公开（公告）日：2014-04-17

  The present invention relates to a process for preparing a catalyst comprising ruthenium nanoparticles supported on a solid support, obtainable by: (a) reacting a ruthenium (0) complex selected from the group consisting of [Ru(diene)(triene)], [Ru(R6)(diene)], and Ru3(CO)12, with a phosphine ligand of formula (I) in the presence of hydrogen; and(b) reacting the ruthenium nanoparticles obtained in Step(a) with a porous solid support, and to the obtained supported phosphine-ruthenium nanoparticles. It is also related to a process for hydrogenating an aromatic compound into the corresponding cyclic saturated or partially unsaturated compound by reaction with hydrogen and in the presence of an effective amount of the obtained supported ruthenium nanoparticles.
• Large P−P Distance Diphosphines and Their Monophosphine Analogues as Ligands in the Palladium-Catalyzed Telomerization of 1,3-Butadiene and Methanol
  作者：Mathieu J.-L. Tschan、Josep-Maria López-Valbuena、Zoraida Freixa、Hélène Launay、Henk Hagen、Jordi Benet-Buchholz、Piet W. N. M. van Leeuwen

  DOI：10.1021/om100980m

  日期：2011.2.28

  The potential of diphosphines based on a dibenzodioxocin or benzofurobenzofuran backbone possessing large P P distances was studied for the selective telomerization of 1,3-butadiene with methanol under commercially relevant process conditions to obtain 1-methoxyocta-2,7-diene (1-MOD). They were found to act as monophosphines. New bulky monophosphine analogues of the same backbone and ferrocene were also evaluated. Several ligands showed improved selectivity and yield compared to the benchmark ligand PPh3 and monoxantphos. Especially 1,6-bis(diphenylphosphino)-5a,10b-dihydro-5a,10b-dimethyl-3,8-dimethylbenzofuro[3,2-b]benzofuran (3) and, 2,10-di-tert-buty1-4-diphenylphosphino-6,12-methano-12H-dibenzo[2,1-d: 1 ',2"-g][1,3]dioxocin (7), a diphosphine and a monophosphine, respectively, stand out as excellent ligands in terms of yield, selectivity, and stability.