(2R,3R,4R,5S,6R)-5-[(2S,3R,4S,5S,6R)-6-[(2-chloro-4-nitrophenoxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3R,4R,5S,6R)-5-[(2S,3R,4S,5S,6R)-6-[(2-chloro-4-nitrophenoxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol
• 化学式: C18H24ClNO13
• 分子量: 497.8
• InChiKey: WKUMKRUDPNZIEN-KFRZSCGFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.5
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  224
• 氢给体数：
  7
• 氢受体数：
  13

文献信息

• Cellulase assay
  申请人：Megazyme IP Limited

  公开号：EP2719758A1

  公开（公告）日：2014-04-16

  The invention involves the development of a substrate and assay procedure for the scientific measurement of cellulase in admixture with other enzymes active on cellulose or 1,4-β-D-gluco-oligosaccharides, or in various levels of purity of the cellulase. This substrate being characterised by the fact that it contains at least 2 glucose units linked β-1,4-, with the reducing end glucose unit linked β- or α- to a compound which exhibits an optically measurable change on cleavage of the bond between it and the adjacent D-glucosyl residue and the non-reducing terminal D-glucosyl unit is covalently linked to a blocking substituent which inhibits cleavage by exo-acting enzymes of the bond between the terminal and non-reducing end, penultimate D-glucose unit.

  本发明涉及开发一种底物和测定程序，用于科学测定纤维素酶与其他对纤维素或 1，4-β-D-葡聚寡糖有活性的酶混合的情况，或不同纯度的纤维素酶。这种底物的特点是，它至少含有 2 个连接在 β-1,4-上的葡萄糖单元，其中还原端的葡萄糖单元与一种化合物连接在 β- 或 α-上，这种化合物在裂解它与相邻 D-葡萄糖残基之间的键时显示出可测量的光学变化，而非还原端的 D-葡萄糖单元与一种阻断取代基共价连接，这种取代基抑制外作用酶裂解末端和非还原端、倒数第二个 D-葡萄糖单元之间的键。
• Cellulase Assay
  申请人：Megazyme IP Limited

  公开号：US20140154721A1

  公开（公告）日：2014-06-05

  The invention involves the development of a substrate and assay procedure for the scientific measurement of cellulase in admixture with other enzymes active on cellulose or 1,4-β-D-cello-oligosaccharides, or in various levels of purity of the cellulase. This substrate being characterised by the fact that it contains at least 2 glucose units linked β-1,4-, with the reducing end glucose unit linked β- or α- to a compound which exhibits an optically measurable change on cleavage of the bond between it and the adjacent D-glucosyl residue and the non-reducing terminal D-glucosyl unit is covalently linked to a blocking substituent which inhibits cleavage by exo-acting enzymes of the bond between the terminal and non-reducing end, penultimate D-glucose unit.