2,2,2-trichloro-N-[(2R,3S,4R,5R,6R)-4-hydroxy-2-[(2S,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis(phenylmethoxy)oxan-2-yl]oxy-5-phenylmethoxy-6-(phenylmethoxymethyl)oxan-3-yl]acetamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2,2-trichloro-N-[(2R,3S,4R,5R,6R)-4-hydroxy-2-[(2S,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis(phenylmethoxy)oxan-2-yl]oxy-5-phenylmethoxy-6-(phenylmethoxymethyl)oxan-3-yl]acetamide
• 化学式: C₄₂H₄₆Cl₃NO₁₁
• 分子量: 847.2
• InChiKey: DRTTYPHCSMGCLG-JENNHALBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  57
• 可旋转键数：
  17
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  154
• 氢给体数：
  4
• 氢受体数：
  11

文献信息

• Glycoconjugates and their use as potential vaccines against infection by Shigella Flexneri
  申请人：INSTITUT PASTEUR

  公开号：EP2724730A1

  公开（公告）日：2014-04-30

  The present invention relates to a conjugate comprising an oligo- or polysaccharide selected from the group consisting of:          (X)x-BCDA}n-(Y)y          (X)x-CDAB}n-(Y)y          (X)x-DABC}n-(Y)y          (X)x-ABCD}n-(Y)y Wherein A, B, C, D, X and Y, x, y and n are as defined in claim 1, said oligo- or polysaccharide being covalently bound to a carrier.

  本发明涉及一种共轭物，包括从以下组中选择的寡糖或多糖：（X）x-BCDA}n-（Y）y，（X）x-CDAB}n-（Y）y，（X）x-DABC}n-（Y）y，（X）x-ABCD}n-（Y）y，其中A、B、C、D、X和Y，x、y和n的定义如权利要求1所述，所述寡糖或多糖与载体共价结合。
• GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI
  申请人：INSTITUT PASTEUR

  公开号：US20150290331A1

  公开（公告）日：2015-10-15

  The present invention relates to a conjugate comprising an oligo- or polysaccharide selected from the group consisting of: (X) x -BCDA} n -(Y) y (X) x -CDAB} n -(Y) y (X) x -DABC} n -(Y) y (X) x -ABCD}n-(Y) y wherein A, B, C, D, X and Y, x, y and n are as defined in claim 1 , said oligo- or polysaccharide being bound to a carrier.

  本发明涉及一种共轭物，该共轭物包括从以下组中选择的寡糖或多糖：(X)x-BCDA}n-(Y)y(X)x-CDAB}n-(Y)y(X)x-DABC}n-(Y)y(X)x-ABCD}n-(Y)y，其中A、B、C、D、X和Y、x、y和n如权利要求1所定义，所述寡糖或多糖与载体结合。
• Glycoconjugates and their use as potential vaccines against infection by Shigella flexneri
  申请人：INSTITUT PASTEUR

  公开号：US10376593B2

  公开（公告）日：2019-08-13

  The present invention relates to a conjugate comprising an oligo- or polysaccharide selected from the group consisting of: (X)x-BCDA}n-(Y)y (X)x-CDAB}n-(Y)y (X)x-DABC}n-(Y)y (X)x-ABCD}n-(Y)y wherein A, B, C, D, X and Y, x, y and n are as defined in claim 1, said oligo- or polysaccharide being bound to a carrier.

  本发明涉及一种共轭物，该共轭物包含选自以下组别的寡糖或多糖：(X)x-BCDA}n-(Y)y (X)x-CDAB}n-(Y)y (X)x-DABC}n-(Y)y (X)x-ABCD}n-(Y)y 其中 A、B、C、D、X 和 Y、x、y 和 n 如权利要求 1 所定义，所述寡糖或多糖与载体结合。