(2R,3S,4S,5R)-2-(hydroxymethyl)-6-sulfanyl-4-(triazol-1-yl)oxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4S,5R)-2-(hydroxymethyl)-6-sulfanyl-4-(triazol-1-yl)oxane-3,4,5-triol
• 化学式: C₈H₁₃N₃O₅S
• 分子量: 263.27
• InChiKey: ZNSYREIXDYEZSC-ZSYVZKQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  122
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• ANTI-TUMOR AGENT OTX-008 TARGETS HUMAN GALECTIN-1
  申请人：REGENTS OF THE UNIVERSITY OF MINNESOTA

  公开号：US20140121278A1

  公开（公告）日：2014-05-01

  Disclosed herein are compositions comprising a galectin-1-targeting compound in a therapeutically effective composition for treating cancer. In an aspect, a galectin-1-targeting compound is OTX-008. Also disclosed herein are methods of making and using such compositions.

  本文披露了包含一种靶向galectin-1的化合物的治疗有效组合物，用于治疗癌症。在一个方面，galectin-1靶向化合物是OTX-008。本文还披露了制备和使用这种组合物的方法。
• [EN] ANTI-TUMOR AGENT OTX-008 TARGETS HUMAN GALECTIN-1<br/>[FR] AGENT ANTITUMORAL OTX-800 QUI CIBLE LA GALECTINE-1 HUMAINE
  申请人：UNIV MINNESOTA

  公开号：WO2014070214A1

  公开（公告）日：2014-05-08

  Disclosed herein are compositions comprising a galectin-1 -targeting compound in a therapeutically effective composition for treating cancer. In an aspect, a galectin-1 -targeting compound is OTX-008. Also disclosed herein are methods of making and using such compositions.