3-Hydroxy-2-methyl-1-phenylpropan-1-one;phosphoroso-(2,4,6-trimethylphenyl)methanone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Hydroxy-2-methyl-1-phenylpropan-1-one;phosphoroso-(2,4,6-trimethylphenyl)methanone
• 英文别名: 3-hydroxy-2-methyl-1-phenylpropan-1-one;phosphoroso-(2,4,6-trimethylphenyl)methanone
• 化学式: C20H23O4P
• 分子量: 358.4
• InChiKey: HZSRWVKWLQUPJD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.54
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  71.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• FIBER COATED NANOPORES
  申请人：TRUSTEES OF BOSTON UNIVERSITY

  公开号：US20160169864A1

  公开（公告）日：2016-06-16

  Provided herein are compositions, compounds, processes, and methods of use of 3D porous coating(s) on or near a nanopore(s) for analysis or detection of charged polymers such as nucleic acids, proteins, protein-nucleic acid complexes, small molecule-biological complexes, polymer-biological complexes, and/or polyelectrolytes.

  本文提供了关于在或靠近纳米孔上使用3D多孔涂层进行带电高分子（如核酸、蛋白质、蛋白质-核酸复合物、小分子-生物复合物、高分子-生物复合物和/或聚电解质）分析或检测的组合物、化合物、过程和使用方法。
• Macroinitiators for hydrophilic coatings on latex and applications thereof
  申请人：TRUSTEES OF BOSTON UNIVERSITY

  公开号：US10617794B2

  公开（公告）日：2020-04-14

  Provided herein are methods comprising the use of a macroinitiator and application protocols to apply a hydrophilic coating to latex, or natural rubber, and compositions resulting from such methods. This coating results in e.g., an increased sense of lubrication when in contact with water or an aqueous solution.

  本文提供的方法包括使用大引发剂和应用规程将亲水涂层涂覆到胶乳或天然橡胶上，以及通过此类方法制备的组合物。这种涂层可在与水或水溶液接触时增加润滑感。
• Injectable tissue supplement
  申请人：TRUSTEES OF BOSTON UNIVERSITY

  公开号：US10821204B2

  公开（公告）日：2020-11-03

  The present invention provides polymers which can be used as tissue supplements or lubricants in vivo. The inventive polymers can be used as tissue-interpenetrating hydrogel supplements, viscosupplements, tribosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pharmaceutical compositions comprising the inventive polymers and methods of using them including, for example, in the treatment of arthritic and injured synovial joints; in reconstruction or cosmetic procedures, intervertebral disc repair, treatment of vocal cord problems, treatment of urinary incontinence, and prevention of adhesion formation following abdominal or gynecological surgery or malfunction of naturally lubricious mucosal tissue.

  本发明提供了可用作体内组织补充剂或润滑剂的聚合物。本发明聚合物可用作组织互穿性水凝胶补充剂、粘度补充剂、三重补充剂、粘弹剂、组织间隙填充剂和/或抗粘剂。本发明还提供了包含本发明聚合物的药物组合物和使用方法，例如用于治疗关节炎和受伤的滑膜关节；用于重建或美容手术、椎间盘修复、治疗声带问题、治疗尿失禁、防止腹部或妇科手术后粘连形成或天然润滑粘膜组织功能失常。
• Fiber coated nanopores
  申请人：Trustees of Boston University

  公开号：US10866230B2

  公开（公告）日：2020-12-15

  Provided herein are compositions, compounds, processes, and methods of use of 3D porous coating(s) on or near a nanopore(s) for analysis or detection of charged polymers such as nucleic acids, proteins, protein-nucleic acid complexes, small molecule-biological complexes, polymer-biological complexes, and/or polyelectrolytes.

  本文提供了在纳米孔上或附近使用三维多孔涂层的组合物、化合物、工艺和方法，用于分析或检测带电聚合物，如核酸、蛋白质、蛋白质-核酸复合物、小分子-生物复合物、聚合物-生物复合物和/或聚电解质。
• INJECTABLE TISSUE SUPPLEMENT
  申请人：Trustees of Boston University

  公开号：EP3071236A1

  公开（公告）日：2016-09-28