6-[[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyamino]-5-methyl-1H-pyrimidin-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-[[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyamino]-5-methyl-1H-pyrimidin-2-one
• 化学式: C₁₁H₁₈N₄O₆
• 分子量: 302.28
• InChiKey: DXPHOECSHMNJMW-PZACJGDYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.5
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  159
• 氢给体数：
  6
• 氢受体数：
  8

文献信息

• Compositions and Methods for the Transfer of a Hexosamine to a Modified Nucleotide in a Nucleic Acid
  申请人：New England Biolads, Inc.

  公开号：US20140127677A1

  公开（公告）日：2014-05-08

  Nucleic acids comprising β-glucosaminyloxy-5-methylcytosine; compositions, kits and methods of producing the nucleic acids using a glycosyltransferase; and methods of using the nucleic acids are described.
• Mapping Cytosine Modifications
  申请人：New England Biolabs, Inc.

  公开号：US20160138079A1

  公开（公告）日：2016-05-19

  Methods, compositions and kits for selectively altering and detecting modified cytosine residues are provided.
• US9200260B2
  申请人：——

  公开号：US9200260B2

  公开（公告）日：2015-12-01
• [EN] COMPOSITIONS AND METHODS FOR THE TRANSFER OF A HEXOSAMINE TO A MODIFIED NUCLEOTIDE IN A NUCLEIC ACID<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR LE TRANSFERT D'UNE HEXOSAMINE À UN NUCLÉOTIDE MODIFIÉ DANS UN ACIDE NUCLÉIQUE
  申请人：NEW ENGLAND BIOLABS INC

  公开号：WO2014074445A1

  公开（公告）日：2014-05-15

  Nucleic acids comprising β-clucosaminyloxy-5-methylcytosine; compositions, kits and methods of producing the nucleic acids using a glycosyltransferase; and methods of using the nucleic acids are described.