N-[(2S,3R,4R,5S,6R)-2-[(2R,3S,4R,5R,6S)-6-[(2R,4R,5R,6S)-5-acetamido-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-5-amino-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[(2S,3R,4R,5S,6R)-2-[(2R,3S,4R,5R,6S)-6-[(2R,4R,5R,6S)-5-acetamido-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-5-amino-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
• 化学式: C₂₈H₅₀N₄O₁₉
• 分子量: 746.7
• InChiKey: IUERQWUTYLFNJM-NPCWRGFTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9.5
• 重原子数：
  51
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  377
• 氢给体数：
  14
• 氢受体数：
  21

文献信息

• PROCESS FOR THE CO-PRODUCTION OF CHITIN, ITS DERIVATIVES AND POLYMERS CONTAINING GLUCOSE, MANNOSE AND/OR GALACTOSE, BY THE FERMENTATION OF THE YEAST PICHIA PASTORIS
  申请人：Carvalho Fernandes De Miranda Reis Maria d'Ascencao

  公开号：US20140120584A1

  公开（公告）日：2014-05-01

  This invention concerns a process for the co-production of glucosamine polymers (chitin, chitosan or any of its derivatives) and polymers containing glucose, mannose and/or galactose, by the high cell density fermentation of the yeast Pichia pastoris in a bioreactor under aerobic conditions, preferably using glycerol byproduct from the biodiesel industry as carbon source. Pure glycerol, pure methanol, glycerol-rich or methanol rich mixtures may also be used as carbon sources. The present invention also concerns P. pastoris fermentation process duly optimized for attaining high cell densities and high cell wall chitin content, as well as polymers containing glucose, mannose and/or galactose.