6-[2-[[[3-[3-[[4-(6-Carboxy-3,4-dihydroxy-5-methyloxan-2-yl)oxy-5-(ethoxyamino)-3-hydroxy-6-methoxyoxan-2-yl]methylamino]propyl]triazol-4-yl]methylamino]methyl]-3-hydroxy-6-methoxy-5-(2-oxoethylamino)oxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-[2-[[[3-[3-[[4-(6-Carboxy-3,4-dihydroxy-5-methyloxan-2-yl)oxy-5-(ethoxyamino)-3-hydroxy-6-methoxyoxan-2-yl]methylamino]propyl]triazol-4-yl]methylamino]methyl]-3-hydroxy-6-methoxy-5-(2-oxoethylamino)oxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid
• 英文别名: 6-[2-[[[3-[3-[[4-(6-carboxy-3,4-dihydroxy-5-methyloxan-2-yl)oxy-5-(ethoxyamino)-3-hydroxy-6-methoxyoxan-2-yl]methylamino]propyl]triazol-4-yl]methylamino]methyl]-3-hydroxy-6-methoxy-5-(2-oxoethylamino)oxan-4-yl]oxy-4,5-dihydroxy-3-methyloxane-2-carboxylic acid
• 化学式: C₃₈H₆₅N₇O₂₀
• 分子量: 940.0
• InChiKey: UIYNPDXBAZKCNC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -9.3
• 重原子数：
  65
• 可旋转键数：
  24
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  375
• 氢给体数：
  12
• 氢受体数：
  26

文献信息

• Amphoteric Materials Based on Crosslinked Hyaluronic Acid, Method of Preparation Thereof, Materials Containing Entrapped Active Agents, Method of Preparation Thereof, and Use of Said Materials
  申请人：CONTIPRO BIOTECH S.R.O.

  公开号：US20140120069A1

  公开（公告）日：2014-05-01

  The present invention describes novel amphoteric materials based on crosslinked hyaluronic acid, according to the general formula (I), and a method of preparation of said materials. Further, the invention relates to the material containing entrapped active agents (e.g. drugs, growth factors etc.) and a method of preparation thereof. Moreover, the present invention relates to the use of said materials for controlled release systems, in tissue engineering, wound dressing or tissue regeneration.

  本发明描述了基于交联透明质酸的新型两性材料，其符合通用式(I)，以及该材料的制备方法。此外，本发明涉及含有包埋活性剂（如药物、生长因子等）的材料及其制备方法。此外，本发明还涉及将所述材料用于控制释放系统、组织工程、伤口敷料或组织再生的用途。